Bacimethrin
Based on 1 Customer Validation
Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth.
For research use only. We do not sell to patients.
- Purity: 98.11%
- CAS No.: 3690-12-8
- Formula: C6H9N3O2
- Molecular Weight:155.15
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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CAS No. 3690-12-8
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Appearance Solid
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Molecular Weight 155.15
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Formula C6H9N3O2
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Color White to off-white
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SMILES
OCC1=CN=C(OC)N=C1N
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Synonyms
NSC 66577
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 4.17 mg/mL (26.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Natalia S Nemeria, et al. Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin. Biochemistry. 2016 Feb 23;55(7):1135-48. [Content Brief]
[2]. J L Zilles, et al. Action of the thiamine antagonist bacimethrin on thiamine biosynthesis. J Bacteriol. 2000 Oct;182(19):5606-10. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4454 mL | 32.2269 mL | 64.4538 mL | 161.1344 mL |
| 5 mM | 1.2891 mL | 6.4454 mL | 12.8908 mL | 32.2269 mL | |
| 10 mM | 0.6445 mL | 3.2227 mL | 6.4454 mL | 16.1134 mL | |
| 15 mM | 0.4297 mL | 2.1485 mL | 4.2969 mL | 10.7423 mL | |
| 20 mM | 0.3223 mL | 1.6113 mL | 3.2227 mL | 8.0567 mL | |
| 25 mM | 0.2578 mL | 1.2891 mL | 2.5782 mL | 6.4454 mL |