2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N16612
    (3S,5S)-[6]-Gingerdiol 143615-76-3 98%
    (3S,5S)-[6]-Gingerdiol is a cestocidal agent. (3S,5S)-[6]-Gingerdiol can be isolate from the roots of ginger. (3S,5S)-[6]-Gingerdiol shows cestocidal activity against H. nana.
    (3S,5S)-[6]-Gingerdiol
  • HY-N16616
    9α-Hydroxysophocarpine 907607-58-3
    9α-Hydroxysophocarpine ((-)-9α-hydroxysophocarpine) is an alkaloid. 9α-Hydroxysophocarpine can be isolated from the rhizomes of Sophora tonkinensis. 9α-Hydroxysophocarpine exhibits antiviral activity against the Coxsackie virus B3 (CVB3).
    9α-Hydroxysophocarpine
  • HY-N16640
    Anol glucoside 120396-85-2 98%
    Anol glucoside is a phenolic glucose glycoside compound found in Cleidion spiciflorum. Anol glucoside has potential antibacterial, anti-inflammatory and antimalarial activities.
    Anol glucoside
  • HY-N16646
    Micrometam A 1622947-22-1
    Micrometam A is a phenethylamine derivative found in Micromelum falcatum. Micrometam A exhibits anti-halogenation activity with a LD50 of 18.5 μg/mL.
    Micrometam A
  • HY-N16665
    6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene 1353042-00-8 98%
    6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene (Compound 6) is a diterpenoid found in Premna obtusifolia with antibacterial activity. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can significantly inhibit the release of the inflammatory mediator NO, with an IC50 value of 29.1 μM. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can be used for the researches of infection and inflammation.
    6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene
  • HY-N16692
    Shizukolidol 90332-92-6
    Shizukolidol is an antimicrobial agent that can be isolated from polyfollicles of Magnolia vovidessi. Shizukolidol shows antibacterial activity against Chryseobacterium sp. Shizukolidol can be used for the research of bacterial infection.
    Shizukolidol
  • HY-N16699
    4'-O-Methyl-8-prenylnaringenin 120727-36-8
    4'-O-Methyl-8-prenylnaringenin is a prenylated flavonoid compound with antibacterial activity, which can be isolated from propolis of the Solomon Islands. 4'-O-Methyl-8-prenylnaringenin exerts its antibacterial activity by enhancing cell penetration and damaging bacterial cell membranes or cell walls. The minimum inhibitory concentrations (MICs) against Staphylococcus aureus, Bacillus subtilis, and Pseudomonas aeruginosa are 32 μg/mL, 32 μg/mL, and 128 μg/mL, respectively.
    4'-O-Methyl-8-prenylnaringenin
  • HY-N1673R
    2,5-Dihydroxybenzaldehyde (Standard) 1194-98-5 98%
    2,5-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,5-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC50 of 500 mg/L[1][2].
    2,5-Dihydroxybenzaldehyde (Standard)
  • HY-N16745
    5-Hydroxynoracronycine 27067-70-5
    5-Hydroxynoracronycine is a selective inhibitor targeting Leishmania, HIV-1 protease, and nitric oxide (NO) production. 5-Hydroxynoracronycine has an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for scavenging DPPH free radicals. 5-Hydroxynoracronycine exerts anti-leishmanial, anti-HIV, antioxidant and antibacterial activities by inhibiting pathogen proliferation, enzyme activity and inflammation-related NO excessive production. 5-Hydroxynoracronycine can be used in the research of leishmaniasis, HIV infection, and inflammation-related diseases.
    5-Hydroxynoracronycine
  • HY-N16760
    Wikstrol B 160963-92-8
    Wikstrol B (compound 5) is a biflavonoid microtubule/tubulin inhibitor and HIV-1 inhibitor. Wikstrol B has an IC50 value of 184 μM for microtubule polymerization and an EC50 of 3.02 μM against HIV-1, acting on early events of HIV-1 replication. Wikstrol B exerts antifungal activity by inducing morphological deformation of Pyricularia oryzae hyphae and exerts anti-mitotic activity by inhibiting microtubule polymerization. Wikstrol B can be used in research related to antifungal, antitumor, and anti-AIDS applications. Wikstrol B can be naturally extracted from the roots of Wikstroemia indica.
    Wikstrol B
  • HY-N16775
    Gylongiposide I 206876-12-2
    Gylongiposide I is a selective inhibitor against the enterovirus EV71 with an EC50 of 1.53 μM. Gylongiposide I exerts antiviral activity by reducing viral protein VP1 expression and viral genomic RNA levels. Gylongiposide I can be used in the development of anti-EV71 drugs related to hand, foot and mouth disease.
    Gylongiposide I
  • HY-N16821
    Hydroxydihydrobovolide 1403940-81-7
    Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection.
    Hydroxydihydrobovolide
  • HY-N16837
    6''-O-β-D-Apiofuranosylastragalin 946827-13-0
    6''-O-β-D-Apiofuranosylastragalin (compound 1) is a flavonoid glycoside that can be naturally extracted from the methanol extract of fresh leaves of Solidago altissima L. (a plant of the genus Solidago in the Asteraceae family). The related methanol extract exhibits antifeedant activity against Thrips palmi and can be used in the research of natural antifeedants for agricultural pest control.
    6''-O-β-D-Apiofuranosylastragalin
  • HY-N16849
    Myristinin A 145904-69-4 98%
    Myristinin A (YM 26567-1) is a trans-isomer flavan compound found in Horsfieldia amygdaline and Myristica cinnamomea. Myristinin A can selectively inhibit COX-2 activity with an IC50 of 16.9 μg/mL. Myristinin A can reduce the production of prostaglandin E2 (PGE2) and inhibit phospholipase A2 (PLA2), thereby blocking the release of inflammatory mediators. Myristinin A can inhibit Candida albicans with an IC50 of 8.8 μg/mL. Myristinin A can be used for the research of inflammation and infection, such as rheumatoid arthritis.
    Myristinin A
  • HY-N16865
    Myristinin B/C 98%
    Myristinin B/C is a mixture of Myristinin B and Myristinin C. Myristinin B/C is a flavan compound found in Horsfieldia amygdaline and Myristica cinnamomea. Myristinin B/C can selectively inhibit COX-2 activity with an IC50 of 2.1 μg/mL. Myristinin B/C can reduce the production of prostaglandin E2 (PGE2) and inhibit phospholipase A2 (PLA2), thereby blocking the release of inflammatory mediators. Myristinin B/C can inhibit Candida albicans with an IC50 of 6 μg/mL. Myristinin B/C can be used for the research of inflammation and infection, such as rheumatoid arthritis.
    Myristinin B/C
  • HY-N16888
    Peruvianoside II 450407-31-5 98%
    Peruvianoside II is a flavanone glucoside compound. Peruvianoside II shows no inhibitory activity against both HIV-1 reverse transcriptase and HIV-1 integrase at concentrations below 100 μM. Peruvianoside II can be extracted from the leaves of Thevetia peruviana.
    Peruvianoside II
  • HY-N16889
    N-Acetylnornuciferine 1942-03-6
    N-Acetylnornuciferine is an aporphine alkaloid, whose family members possess potential antibacterial, antiviral, antioxidant, or anticancer activities. N-Acetylnornuciferine can be extracted from the dried roots of Liriodendron tulipifera (American tulip tree, a plant of the Magnoliaceae family) using ethanol.
    N-Acetylnornuciferine
  • HY-N17236
    Forsyshiyanine A 2767053-65-4 98%
    Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC50 of 4.5 μM against respiratory syncytial virus (RSV) and an IC50 of 7.3 μM against influenza A virus (H1N1). Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection.
    Forsyshiyanine A
  • HY-N17260
    Phellandral 21391-98-0 98%
    Phellandral is an aldehyde compound that can be found in Eucalyptus camaldulensis and Thymus seravschanicus. The phellandral-containing eucalyptus essential oil exhibits significant inhibitory effects on various plant pathogenic fungi, especially on Aspergillus flavus. Phellandral, together with other oxygenated monoterpenoids, constitutes an important basis for the antibacterial activity of the essential oil.
    Phellandral
  • HY-N17297
    Leotiomycene C 2293113-73-0
    Leotiomycene C is an isoprenylated bisresorcinol natural product present in the freshwater fungus Helotiales sp. Leotiomycene C inhibits the quorum sensing system of methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA), with an IC₅₀ of 6.3-12.5 μM. Leotiomycene C is applicable to research related to MRSA infections.
    Leotiomycene C
Cat. No. Product Name / Synonyms Application Reactivity