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  3. HIV
  4. Hydroxydihydrobovolide

Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection.

For research use only. We do not sell to patients.

Hydroxydihydrobovolide

Hydroxydihydrobovolide Chemical Structure

CAS No. : 1403940-81-7

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Hydroxydihydrobovolide Related Antibodies

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Description

Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection[1].

IC50 & Target[1]

HIV-1

122.7 μM (IC50)

In Vitro

Hydroxydihydrobovolide (Compound HDB) (0.01-50 μM; 48 h) has significant cytotoxicity on SH-SY5Y cells at 50 μM[1].
Hydroxydihydrobovolide inhibits HIV-1 replication with an IC50 of 122.7 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hydroxydihydrobovolide Related Antibodies

Cell Viability Assay[1]

Cell Line: SH-SY5Y human neuroblastoma cells
Concentration: 0.01, 0.1, 1, 10, 50 μM
Incubation Time: 48 h
Result: Did not cause a statistically significant decrease in SH-SY5Y cell viability at 0.01-10 μM.
Significantly inhibited SH-SY5Y cell growth at 50 μM.
Molecular Weight

198.26

Formula

C11H18O3
CAS No.
SMILES

CCCCC[C@]1(C(C)=C(C(O1)=O)C)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Hydroxydihydrobovolide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroxydihydrobovolide1403940-81-7HIVHuman immunodeficiency virusPortulaca oleracea L.neuroblastomaanti-HIVSH-SY5Y cellsInhibitorinhibitorinhibit

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