Hydroxydihydrobovolide
Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection.
For research use only. We do not sell to patients.
- CAS No.: 1403940-81-7
- Formula: C11H18O3
- Molecular Weight:198.26
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
HIV-1 122.7 μM (IC50) |
Hydroxydihydrobovolide (Compound HDB) (0.01-50 μM; 48 h) has significant cytotoxicity on SH-SY5Y cells at 50 μM[1].
Hydroxydihydrobovolide inhibits HIV-1 replication with an IC50 of 122.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:SH-SY5Y human neuroblastoma cells
-
Concentration:0.01, 0.1, 1, 10, 50 μM
-
Incubation Time:48 h
-
Result:Did not cause a statistically significant decrease in SH-SY5Y cell viability at 0.01-10 μM.
Significantly inhibited SH-SY5Y cell growth at 50 μM.
Chemical Information
-
CAS No. 1403940-81-7
-
Molecular Weight 198.26
-
Formula C11H18O3
-
SMILES
CCCCC[C@]1(C(C)=C(C(O1)=O)C)O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydroxydihydrobovolide Related Classifications
HY-N16821 Related Classifications
Powered by Bioz