2. Anti-infection Metabolic Enzyme/Protease
  3. Parasite HIV HIV Protease
  4. 5-Hydroxynoracronycine

5-Hydroxynoracronycine is a selective inhibitor targeting Leishmania, HIV-1 protease, and nitric oxide (NO) production. 5-Hydroxynoracronycine has an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for scavenging DPPH free radicals. 5-Hydroxynoracronycine exerts anti-leishmanial, anti-HIV, antioxidant and antibacterial activities by inhibiting pathogen proliferation, enzyme activity and inflammation-related NO excessive production. 5-Hydroxynoracronycine can be used in the research of leishmaniasis, HIV infection, and inflammation-related diseases.

For research use only. We do not sell to patients.

5-Hydroxynoracronycine

5-Hydroxynoracronycine Chemical Structure

CAS No. : 27067-70-5

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5-Hydroxynoracronycine Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

5-Hydroxynoracronycine is a selective inhibitor targeting Leishmania, HIV-1 protease, and nitric oxide (NO) production. 5-Hydroxynoracronycine has an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for scavenging DPPH free radicals. 5-Hydroxynoracronycine exerts anti-leishmanial, anti-HIV, antioxidant and antibacterial activities by inhibiting pathogen proliferation, enzyme activity and inflammation-related NO excessive production. 5-Hydroxynoracronycine can be used in the research of leishmaniasis, HIV infection, and inflammation-related diseases[1][2].

IC50 & Target

HIV-1

 

In Vitro

The 48-hour EC50 of 5-Hydroxynoracronycine against Leishmania infantum promastigotes is 4.42 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Hydroxynoracronycine Related Antibodies
Molecular Weight

323.34

Formula

C19H17NO4
CAS No.
SMILES

O=C1C2=C(N(C)C3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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5-Hydroxynoracronycine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Hydroxynoracronycine27067-70-5ParasiteHIVHIV ProteaseHuman immunodeficiency virusInhibitorinhibitorinhibit

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