2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-107852
    Demeton-S-methyl sulfone 17040-19-6 98%
    Demeton-S-methyl sulfone is an organophosphorus insecticide metabolite.Demeton-S-methyl sulfone serves as a substrate for metabolic breakdown.Demeton-S-methyl sulfone forms via oxidation of demeton S-methyl sulfoxide in sugar-beet cell suspension cultures.Demeton-S-methyl sulfone undergoes thioester bond cleavage, producing ethanethiols that convert into S-methylated compounds or S-glucosides.
    Demeton-S-methyl sulfone
  • HY-108002
    A 33903 70890-53-8 98%
    A 33903 is a respiratory syncytial virus (RSV) replication inhibitor. A 33903 can be used for the research of RSV-infection.
    A 33903
  • HY-108018
    MK 6325 1263814-52-3 98%
    MK 6325 is a HCV NS3/4a protease inhibitor. MK 6325 displays the broad genotype and mutant potency. MK 6325 can be used for the research of infection.
    MK 6325
  • HY-108021
    HT-61 936622-80-9 98%
    HT-61 is a quinolone antibacterial agent. HT-61 exhibits bactericidal activity against gram-positive bacteria including methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). HT-61 can enhance the effect of Tobramycin (HY-B0441) against Pseudomonas aeruginosa.
    HT-61
  • HY-108023
    SP187 hydrochloride 1333144-07-2 98%
    SP187 hydrochloride (MON-DNJ hydrochloride; UV4 hydrochloride) is an orally active, host-targeting iminosaccharide against filovirus infection. SP187 hydrochloride inhibits endoplasmic reticulum glucosidase. SP187 hydrochloride exhibits antiviral and Dengue Virus activity in vivo. SP187 hydrochloride can be used in antiviral and dengue research.
    SP187 hydrochloride
  • HY-108029
    Deldeprevir sodium 1298053-61-8 98%
    Deldeprevir (ACH-2684; Neceprevir) sodium is a HCV NS3/4A protease inhibitor and resistance inhibitor. Deldeprevir sodium exhibits activity against wild-type genotype 1a and 1b HCV, including mutant strains resistant to other NS3 protease inhibitors. Deldeprevir sodium blocks the emergence of HCV mutant strains resistant to ACH-3422 in vitro, with enhanced efficacy when used in triple combination with ACH-3422 and ACH-3102 (HY-124182). Deldeprevir sodium shows additive antiviral potency when combined with ACH-3422, and exerts antiviral activity against HCV replicons carrying ACH-3102. Deldeprevir sodium is applicable to research related to hepatitis C.
    Deldeprevir sodium
  • HY-108053
    CDRI-97/78 372960-05-9 98%
    CDRI-97/78 is an antimalarial agent. CDRI-97/78 has phototoxicity and can induce cell apoptosis and G2/M phase arrest. CDRI-97/78 can be used for the research of infection.
    CDRI-97/78
  • HY-108080
    BAL-0019764 404824-79-9 98%
    BAL-0019764 is an iron carrier monocyclic β-lactam with broad-spectrum β-lactase inhibition ability. BAL-0019764 has inhibitory activity against various Gram negative bacteria. BAL-0019764 is commonly used in the study of bacterial infections.
    BAL-0019764
  • HY-108191
    Paldimycin A 101411-70-5 98%
    Paldimycin A (Antibiotic 273a1α) is an antibiotic derived from Streptomyces paulus, primarily targeting Gram-positive bacteria. Paldimycin A exerts its antibacterial effects by interfering with bacterial protein synthesis and cell membrane function.
    Paldimycin A
  • HY-108255
    HIV-1 inhibitor-60 1443461-21-9 98%
    HIV-1 inhibitor-60 (compound 45) is an HIV inhibitor with the potential for the research of infection diseases.
    HIV-1 inhibitor-60
  • HY-10852A
    Arterolane maleate 959520-73-1 98%
    Arterolane (OZ 277) (maleate) is an orally active antimalarial. Arterolane exhibits potent activity against erythrocytic stages of P. falciparum and Plasmodium vivax. Arterolane (maleate) is promising for research of falciparum malaria.
    Arterolane maleate
  • HY-10852R
    Arterolane (Standard) 664338-39-0
    Arterolane (Standard) is the analytical standard of Arterolane. This product is intended for research and analytical applications. Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
    Arterolane (Standard)
  • HY-10870R
    RO-9187 (Standard) 876708-03-1
    RO-9187 (Standard) is the analytical standard of RO-9187 (HY-10870). This product is intended for research and analytical applications. RO-9187 is a potent inhibitor of HCV virus replication with an IC50 of 171 nM. RO-9187 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    RO-9187 (Standard)
  • HY-108930
    HI-207 244268-79-9 98%
    HI-207 is a non-nucleoside reverse transcriptase inhibitor. HI-207 has anti-HIV activity (PBMC/p24 inhibition assay: IC50 = 0.27 μM). HI-207 can be used for HIV infection research.
    HI-207
  • HY-108954
    A-30912A nucleus hydrochloride 1029890-89-8 99.84%
    A-30912A nucleus hydrochloride is the product of Echinocandin B (ECB) deacylase-catalyzed antifungal agent A-30912A (HY-125723).
    A-30912A nucleus hydrochloride
  • HY-108988
    Albicidin 1622253-00-2 98%
    Albicidin is a peptide antibiotic with phytotoxic activity. Albicidin potently inhibits bacterial and plant DNA gyrase at nanomolar concentrations, blocks DNA replication, and exhibits excellent antibacterial efficacy against multidrug-resistant bacteria. Albicidin possesses bactericidal activity against Gram-positive and Gram-negative microorganisms, and acts as a virulence factor for the systemic plant infection by Xanthomonas albilineans. Albicidin can be used in studies related to bacterial infections and sugarcane leaf blight.
    Albicidin
  • HY-108989
    FMDP 96920-07-9 98%
    FMDP is an inhibitor of GlcN-6-P Synthase with an anti-candidal activity. FMDP can be covalently attached to a polyethylene glycol as a nanoparticle shows strong anticancer activity.
    FMDP
  • HY-109072
    Riamilovir 123606-06-4 98%
    Riamilovir is an antiviral drug whose activity is primarily directed against RNA viruses. Riamilovir acts directly on the virus's RNA-dependent RNA polymerase, thereby preventing the virus from replicating. This mechanism allows Riamilovir to effectively reduce the amount of virus, accelerate the relief of symptoms, and help reduce the severity of the disease. Riamilovir can be used in the study of acute respiratory viral infections caused by new variants of SARS-CoV-2.
    Riamilovir
  • HY-109125
    SPK-843 143483-67-4 98%
    SPK-843 is an antifungal agent. SPK-843 shows inhibitory activity against A. fumigatus MF-13, A. flavus TIMM 0057, and A. niger TIMM 2814 with MICs of 0.5 μg/mL, 0.25 μg/mL, and 0.0625 μg/mL, respectively. SPK-843 exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis. SPK-843 can be used for the research of related fungal infections.
    SPK-843
  • HY-10964R
    Vadimezan (Standard) 117570-53-3 98%
    Vadimezan (Standard) (DMXAA (Standard)) is the analytical standard of Vadimezan (HY-10964). This product is intended for research and analytical applications. Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities.
    Vadimezan (Standard)
Cat. No. Product Name / Synonyms Application Reactivity