A-30912A nucleus hydrochloride

Cat. No.: HY-108954 Purity: 99.84%: Data Sheet
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A-30912A nucleus hydrochloride is the product of Echinocandin B (ECB) deacylase-catalyzed antifungal agent A-30912A (HY-125723).

For research use only. We do not sell to patients.

A-30912A nucleus hydrochloride Chemical Structure

CAS No. : 1029890-89-8

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	Get quote
1 g	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of A-30912A nucleus hydrochloride:

Echinocandin B nucleus Get quote

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Purity & Documentation
References
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Description

A-30912A nucleus hydrochloride is the product of Echinocandin B (ECB) deacylase-catalyzed antifungal agent A-30912A (HY-125723)^[1].

In Vitro

Echinocandin B (ECB), obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-D-glucan synthase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

834.27

Formula

C₃₄H₅₂ClN₇O₁₅

CAS No.

1029890-89-8

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, stored under nitrogen, away from moisture

In solvent	-80°C	1 year
	-20°C	6 months

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (119.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1987 mL	5.9933 mL	11.9865 mL
5 mM	0.2397 mL	1.1987 mL	2.3973 mL
10 mM	0.1199 mL	0.5993 mL	1.1987 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.84%

Select Batch:

Data Sheet (280 KB) SDS (394 KB)

COA (262 KB) HNMR (141 KB) RP-HPLC (227 KB) LCMS (102 KB)

Handling Instructions (2659 KB)

References

[1]. Lei Shao, et al. Efficient bioconversion of echinocandin B to its nucleus by overexpression of deacylase genes in different host strains. Appl Environ Microbiol. 2013 Feb;79(4):1126-33. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1987 mL	5.9933 mL	11.9865 mL	29.9663 mL
	5 mM	0.2397 mL	1.1987 mL	2.3973 mL	5.9933 mL
	10 mM	0.1199 mL	0.5993 mL	1.1987 mL	2.9966 mL
	15 mM	0.0799 mL	0.3996 mL	0.7991 mL	1.9978 mL
	20 mM	0.0599 mL	0.2997 mL	0.5993 mL	1.4983 mL
	25 mM	0.0479 mL	0.2397 mL	0.4795 mL	1.1987 mL
	30 mM	0.0400 mL	0.1998 mL	0.3996 mL	0.9989 mL
	40 mM	0.0300 mL	0.1498 mL	0.2997 mL	0.7492 mL
	50 mM	0.0240 mL	0.1199 mL	0.2397 mL	0.5993 mL
	60 mM	0.0200 mL	0.0999 mL	0.1998 mL	0.4994 mL
	80 mM	0.0150 mL	0.0749 mL	0.1498 mL	0.3746 mL
	100 mM	0.0120 mL	0.0599 mL	0.1199 mL	0.2997 mL