2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105215
    FK888 138449-07-7 98%
    FK888 is a potent, selective, and high affinity dipeptide NK1 receptor antagonist. FK888 displaces [3H]-SP binding with a Ki value of 0.69 nM and 0.45 microM. FK888 also inhibits SP-induced airway oedema in guinea-pig after both intravenous and oral administration.
    FK888
  • HY-105220
    WY-47766 134217-27-9 98%
    WY-47766(OST-766) is aproton pumpinhibitor.
    WY-47766
  • HY-105290
    DRF-4848 376588-53-3 98%
    DRF-4848 is a COX-2 inhibitor. DRF-4848 can be used for the research of inflammation.
    DRF-4848
  • HY-105324
    GRC-6211 1166398-35-1 98%
    GRC-6211 is an orally active and selective TRPV1 antagonist. GRC-6211 exhibits anti-inflammation effect.
    GRC-6211
  • HY-105325
    SB-219994 177785-17-0 98%
    SB-219994 is a peroxisome proliferator-activated receptors (PPARs) agonists. SB-219994 can inhibit airway neutrophilia and associated chemoattractants/survival factors. SB-219994 exhibits anti-inflammation effec.
    SB-219994
  • HY-105358
    CP-288886 221332-74-7 98%
    CP-288886 is a cysLT1 receptor antagonist with a Ki value of 0.004 μM. CP-288886 exhibits comparable activity to Zafirlukast (HY-17492) and Pranlukast (HY-B0290). CP-288886 inhibits calcium mobilization with an IC50 of 0.0005 μM in human U937 cells. CP-288886 has high oral bioavailability. CP-288886 possesses anti-asthmatic activity in a guinea pig asthma model and can be used for the research of diseases such as asthma.
    CP-288886
  • HY-105360
    GI-129471 130370-59-1 98%
    GI-129471 is a MMP inhibitor. GI-129471 exhibits inhibitory activity against cancer cell invasion. GI-129471 can completely block the enhanced production of IgE and IgG1 by mouse B cells induced by rat mast cell protease-I (RMCP-I). GI-129471 can be used for the study of cancer and mast cell chymase-regulated immunological processes.
    GI-129471
  • HY-105372
    PNU-103657 179556-43-5 98%
    PNU-103657 (Compound 13) is an orally active reverse transcriptase inhibitor (IC50 = 0.51 μM (WT)). PNU-103657 has antiviral activity. PNU-103657 can be used in research on infections and immune system diseases such as HIV infection.
    PNU-103657
  • HY-105396
    L 670630 133174-26-2 98%
    L 670630 is a potent and orally active inhibitor of 5-lipoxygenase, with the IC50 of 23 nM.
    L 670630
  • HY-105400
    NIP 502 108616-42-8 98%
    NIP 502 is a pyridazinone derivative with orally active anti-inflammation and anti-immunology effects. NIP 502 can be used for the research of asthma.
    NIP 502
  • HY-105407
    GW 273629 250599-60-1 98%
    GW 273629 is a selective nitric oxide synthase inhibitor. GW 273629 exhibits anti-inflammation effect.
    GW 273629
  • HY-105410
    OT-7100 174858-27-6 98%
    OT-7100 is an orally active analgesic agent. OT-7100 inhibits hyperalgesia possibly by enhancing adenosinergic neurotransmission in the dorsal horn. OT-7100 can be used for the researches of inflammation, neurological and metabolic disease such as diabetes2].
    OT-7100
  • HY-105424
    Florifenine 83863-79-0 98%
    Florifenine is a selective cyclooxygenase (COX) inhibitor with anti-inflammatory activity. Florifenine inhibits TXB2 in human whole blood with an IC50 of 32.5 nM. Florifenine exhibits anti-inflammatory effects in ear oedema. Florifenine inhibits neutrophil migration and reduces PGE2 levles in the inflamed ears. Florifenine inhibits leukocyte migration and PGE2 levels in the air pouch inflammation induced by Zymosan (HY-159069). Florifenine can be used for anti-inflammatory research.
    Florifenine
  • HY-105426
    L-695499 150200-28-5 98%
    L-695499 is a potent and orally active leukotriene D4 receptor antagonist. L-695499 can be used for the researches of inflammation and immunology.
    L-695499
  • HY-105455
    NCX-530 204268-63-3 98%
    NCX-530 is an Indomethacin (HY-14397) molecule chemically conjugated with a NO moiety. NCX-530 can release NO. NCX-530 can inhibit cancer cells proliferation and induce apoptosis. NCX-530 can be used for the researches of cancer and inflammation.
    NCX-530
  • HY-105462
    MDL 105212A 167261-60-1 98%
    MDL 105212A is a potent and orally active nonpeptide neurokinin receptor (NK-1/NK-2) tachykinin receptor antagonist. MDL 105212A can be used for the researches of inflammation, immunology and neurological disease, such as asthma.
    MDL 105212A
  • HY-105480
    SKF 104351 111908-94-2 98%
    SKF 104351 is an orally active cytokine suppressive anti-inflammatory drug. SKF 104351 can inhibit TNF-α production.
    SKF 104351
  • HY-105483
    MDL 43291 129357-91-1 98%
    MDL 43291 is a competitive leukotriene (LT) receptor antagonist. MDL 43291 antagonize LTD4 and LTE4 with pA2 of 6.7. MDL 43291 does not antagonize histamine, carbachol or substance P. MDL 43291 can be used for the researches of inflammation and immunology, such as asthma.
    MDL 43291
  • HY-105488
    MDL 201112 142130-73-2 98%
    MDL 201112 is a carbocyclic nucleoside. MDL 201112 can decrease TNF-α production and inhibit MHC class II Ia+ antigen expression. MDL 201112 can be used for the research of inflammation and immunology.
    MDL 201112
  • HY-105504
    CI-986 130116-16-4 98%
    CI-986 is a dual inhibitor of COX and 5-LOX. CI-986 can prevent the coronary vasoconstriction and the increased production of LTB(4) and LTC(4). CI-986 also has anti-inflammatory and analgesic effects. CI-986 can be used for the researches of inflammation and cardiovascular disease, such as arthritis.
    CI-986
Cat. No. Product Name / Synonyms Application Reactivity