OT-7100
OT-7100 is an orally active analgesic agent. OT-7100 inhibits hyperalgesia possibly by enhancing adenosinergic neurotransmission in the dorsal horn. OT-7100 can be used for the researches of inflammation, neurological and metabolic disease such as diabetes2].
For research use only. We do not sell to patients.
- CAS No.: 174858-27-6
- Formula: C20H24N4O4
- Molecular Weight:384.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Adenosine Receptor Isoforms
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Biological Activity
OT-7100 (10-100 mg/kg, p.o., daily for 21 days) increases the nociceptive threshold in diabetic rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 174858-27-6
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Molecular Weight 384.43
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Formula C20H24N4O4
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SMILES
O=C(C1=CC(OC)=C(OC)C(OC)=C1)NC2=CC(CCCC)=NC3=CC=NN23
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yasuda T, et al. A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception. Jpn J Pharmacol. 2001 Nov;87(3):214-25. [Content Brief]
[2]. Miki S, et al. Antinociceptive effect of the novel compound OT-7100 in a diabetic neuropathy model. Eur J Pharmacol. 2001 Nov 2;430(2-3):229-34. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)