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Cat. No.: HY-105426

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L-695499

L-695499 is a potent and orally active leukotriene D4 receptor antagonist. L-695499 can be used for the researches of inflammation and immunology.

For research use only. We do not sell to patients.

CAS No.: 150200-28-5
Formula: C₃₄H₃₆ClNO₃S
Molecular Weight:574.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

L-695499 Chemical Structure

CAS No.: 150200-28-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

L-695499 is a potent and orally active leukotriene D4 receptor antagonist. L-695499 can be used for the researches of inflammation and immunology^[1].

IC₅₀ & Target^[1]

LTD₄

All Leukotriene Receptor Isoforms :

In Vivo

L-695499 (100 mg/kg, p.o., 4 days) increases fatty acyl Co-A oxidase activity in monkeys^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 150200-28-5
Molecular Weight 574.17
Formula C₃₄H₃₆ClNO₃S
SMILES

CC(C)(O)C(C=CC=C1)=C1CC[C@H](SC[C@@H](CC)C(O)=O)C2=CC=CC(/C=C/C3=NC4=CC(Cl)=CC=C4C=C3)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Labelle M, et al. The discovery of a new structural class of potent orally active leukotriene D4 antagonists[J]. Bioorganic & medicinal chemistry letters, 1992, 2(9): 1141-1146.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References

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L-695499

All Leukotriene Receptor Isoforms