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Cat. No.: HY-105290

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DRF-4848

DRF-4848 is a COX-2 inhibitor. DRF-4848 can be used for the research of inflammation.

For research use only. We do not sell to patients.

CAS No.: 376588-53-3
Formula: C₁₇H₁₂F₂O₄S
Molecular Weight:350.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

DRF-4848 Chemical Structure

CAS No.: 376588-53-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

DRF-4848 is a COX-2 inhibitor. DRF-4848 can be used for the research of inflammation^[1].

IC₅₀ & Target^[1]

COX-2

All COX Isoforms :

Chemical Information

CAS No. 376588-53-3
Molecular Weight 350.34
Formula C₁₇H₁₂F₂O₄S
SMILES

O=C1C(C2=CC=C(F)C=C2)=C(C3=C(C=C(S(C)(=O)=O)C=C3)F)CO1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kallem RR, et al. Validation of a simple HPLC method for DRF-4848, a novel COX-2 inhibitor suitable for pharmacokinetic application in rats. Biomed Chromatogr. 2006 Dec;20(12):1289-94. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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