Inflammation/Immunology

Related Products

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Inflammation/Immunology Related Products (19639)
Antibodies (104)
Related Compound Screening Libraries (4)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-N7114AR

Chloramphenicol succinate sodium (Standard)	982-57-0
Chloramphenicol succinate sodium (Standard) is the analytical standard of Chloramphenicol succinate sodium. This product is intended for research and analytical applications. Chloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC₅₀ of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease.

HY-N7122AR

Thymopentin acetate (Standard)	89318-88-7	98%
Thymopentin (acetate) (Standard) is the analytical standard of Thymopentin (acetate) (HY-N7122A). This product is intended for research and analytical applications. Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs).

HY-P0036S2

Octreotide-d8	1240797-41-4	98%
Octreotide-d₈ (SMS 201-995-d₈) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.

HY-P0036S3

Octreotide-13C9,15N		98%
Octreotide-¹³C₉,¹⁵N (SMS 201-995-¹³C₉,¹⁵N) is ¹³C and ¹⁵N labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.

HY-P0036S4

Octreotide-d8 acetate		98%
Octreotide-d₈ (acetate) (SMS 201-995-d₈ (acetate)) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.

HY-P10639A

C5aR2 agonist P32 acetate		98%
C5aR2 agonist P32 (Ac-RHYPYWR-OH) acetate is a C5aR2-selective agonist. C5aR2 agonist P32 acetate has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo.

HY-P990119

Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58)		98%
Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58) is an anti-mouse Kappa Immunoglobulin Light Chain IgG1 monoclonal antibody. Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58) can reduce the phosphorylation levels of Src and Syk in B cells and the antigen presentation ability of B cells. Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58) can be used for research on immunology.

HY-P990137

Anti-Rat CD28 Antibody (JJ319)		98%
Anti-Rat CD28 Antibody (JJ319) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to rat CD28. Anti-Rat CD28 Antibody (JJ319) activates T cells in the presence of T cell receptor-stimulation. Anti-Rat CD28 Antibody (JJ319) can be used for the researches of inflammation and immunology, such as transplantation and neuritis.

HY-P990152

Anti-Mouse TIM-4 Antibody (RMT4-54)		98%
Anti-Mouse TIM-4 Antibody (RMT4-54) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse TIM-4. Anti-Mouse TIM-4 Antibody (RMT4-54) reacts with mouse T cell immunoglobulin and mucin domain 4 (TIM-4) and blocks TIM-4 signaling. Anti-Mouse TIM-4 Antibody (RMT4-54) inhibits phagocytosis of apoptotic cells. Anti-Mouse TIM-4 Antibody (RMT4-54) can be used for the researches of immunology and metabolic disease.

HY-P990163

Anti-Mouse Siglec-H Antibody (440c)		98.45%
Anti-Mouse Siglec-H Antibody (440c) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse Siglec-H. Anti-Mouse Siglec-H Antibody (440c) recognizes sialic acid-binding immunoglobulin (Ig)-like lectin family (Siglec-H) selectively expressing on plasmacytoid DCs and interferon–producing cells. Anti-Mouse Siglec-H Antibody (440c) can be used for the researches of inflammation and immunology, such as colitis.

HY-P990164

Anti-Mouse RGMb Antibody (307.9D1)		98%
Anti-Mouse RGMb Antibody (307.9D1) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse RGMb. Anti-Mouse RGMb Antibody (307.9D1) blocks RGMb binding to PD-L2. Anti-Mouse RGMb Antibody (307.9D1) can be used for the researches of cancer inflammation and immunology, such as acute myeloid leukemia (AML) and graft versus-host disease (GVHD).

HY-P990170

Anti-Mouse PD-L2/B7-DC Antibody (TY25)
Anti-Mouse PD-L2/B7-DC Antibody (TY25) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse PD-L2/B7-DC. Anti-Mouse PD-L2/B7-DC Antibody (TY25) blocks PD-L2 binding to PD-1 and blocks PD-1 signaling. Anti-Mouse PD-L2/B7-DC Antibody (TY25) can be used for the researches of inflammation and immunology, such as conjunctivitis and transplantation.

HY-P990176

Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86)		98%
Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86) is an anti-mouse OX40/CD134 (LALA-PG) IgG2a monoclonal antibody. Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86) is a chimeric antibody of the original OX86 antibody (HY-P990115). Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86) can significantly enhance the generation of antigen-specific effector T cells. Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86) can be used for research on cancer .

HY-P990179

Anti-Mouse NKG2AB6 Antibody (16A11)		98%
Anti-Mouse NKG2AB6 Antibody (16A11) is an anti-mouse NKG2AB6 IgG2b monoclonal antibody. Anti-Mouse NKG2AB6 Antibody (16A11) reduces depletion of antigen-specific CD8 T cells. Anti-Mouse NKG2AB6 Antibody (16A11) can be used for research on cancer such as lung cancer and colon cancer.

HY-P990185

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)		98%
Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/rat MHC Class II. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) reacts with mouse MHC Class II alloantigen I-Ek and the rat MHC class II alloantigen RT1D. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) blocks antigen presentation. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) can be used for the research of immunology and cancer.

HY-P990197

Anti-Mouse MAdCAM-1 Antibody (MECA-367)		98%
Anti-Mouse MAdCAM-1 Antibody (MECA-367) is an anti-mouse MAdCAM-1 IgG2a monoclonal antibody. Anti-Mouse MAdCAM-1 Antibody (MECA-367) significantly inhibits the migration of pig peripheral blood lymphocytes (PBL) by blocking the function of MAdCAM-1. Anti-Mouse MAdCAM-1 Antibody (MECA-367) selectively inhibits B cell migration to exacerbate inflammation. Anti-Mouse MAdCAM-1 Antibody (MECA-367) can be used for researches on inflammation, metabolic conditions and xenotransplantation such as colitis and diabetes.

HY-P990204

Anti-Mouse LAG-3 (D265A) Antibody (C9B7W)		98%
Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) is an anti-mouse LAG-3 IgG1 monoclonal antibody. Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) is a chimeric antibody of the original C9B7W antibody (HY-P99141). Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) contains the D265A mutation region. Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) can be used for research on cancer.

HY-P990240

Anti-Mouse GITR (LALA-PG) Antibody (DTA-1)		98.19%
Anti-Mouse GITR (LALA-PG) Antibody (DTA-1) is an anti-mouse GITR IgG2a monoclonal antibody. Anti-Mouse GITR (LALA-PG) Antibody (DTA-1) is a chimeric antibody of the original DTA-1 antibody (HY-P990124). Anti-Mouse GITR (LALA-PG) Antibody (DTA-1) contains the LALA-PG mutation region. Anti-Mouse GITR (LALA-PG) Antibody (DTA-1) can be used for research on cancer and allergic conditions. The recommed isotype control of Anti-Mouse GITR (LALA-PG) Antibody (DTA-1) is Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990252

Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2)		98%
Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) is an anti-mouse Delta-like protein 4/DLL4 IgG monoclonal antibody. Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) can reduce angiogenesis and density by blocking the DLL4-Notch signaling pathway. Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) reduces inflammatory response by decreasing NF-κB activity and pro-inflammatory factors (IL-1β, iNOS, IL-6) levels. Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) can inhibit Th17 cell differentiation and IL-17A production. Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) can reduce macrophage infiltration and alleviate insulin resistance. Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) can be used for researches on inflammation, metabolic conditions and cancer such as atherosclerosis, pancreatic cancer and asthma.

HY-P990253

Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5)		98%
Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) is an anti-mouse Delta-like protein 1/DLL1 IgG monoclonal antibody. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) can reverse the inhibition of Treg cells. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) can inhibit the upregulation of GLT-1 expression induced by endothelial cells. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) reduces autoimmune response by reducing B cell activation. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) can be used for research on inflammation conditions such as lupus nephritis.

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Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology Related Products (19639)

Antibodies (104)

Related Compound Screening Libraries (4)

Inflammation/Immunology Related Products (19639):