2. Others

Others

Others

Related Products

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There are a number of inhibitors, agonists, and antagonists which we cannot make precise classification because the research area is still unknown.

Others Related Products (73873):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-116128
    Brassilexin 119752-76-0 98%
    Brassilexin is a sulphur-containing phytoalexin, that can be isolated from Brassica juncea L., (cruciferae).
    Brassilexin
  • HY-116131
    DAC-2-25 1675245-09-6 98%
    DAC-2-25 is a molecule that causes a homeotic transformation of body column into tentacle zone.
    DAC-2-25
  • HY-116132
    Kotanin 27909-08-6 98%
    Kotanin is a metabolite of Aspergillus glaucus.
    Kotanin
  • HY-116137
    Nav1.7-IN-17 1235403-87-8 98%
    Nav1.7-IN-17 is an active compound.
    Nav1.7-IN-17
  • HY-116138
    RG-14467 137515-05-0 98%
    RG-14467 is an epidermal growth factor receptor tyrosine kinase inhibitor with activity that inhibits enzyme activity. RG-14467 has similar inhibition kinetics to Lavendustin-A, with a dissociation constant of 3.4μM for the initial rapidly formed complex and an overall dissociation constant estimated to be less than or equal to 30nM, and is a partially competitive inhibitor for ATP.
    RG-14467
  • HY-116148
    AHR-11797 125992-09-8 98%
    AHR-11797 is an active compound.
    AHR-11797
  • HY-116149
    A-424274 1335145-56-6 98%
    A-424274 is a positive allosteric modulator of the α4β2 neuronal nicotinic acetylcholine receptor with activity to enhance the efficacy of analgesics. A-424274 selectively enhances the potency of a range of nicotinic acetylcholine receptor agonists at the α4β2 receptor and, in preclinical models, co-administration with an α4β2 PAM significantly enhances the analgesic efficacy of ABT-594 at clinically well-tolerated doses in humans.
    A-424274
  • HY-116161
    Bimatoprost isopropyl ester 130273-87-9 98%
    15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
    Bimatoprost isopropyl ester
  • HY-116163
    ML350 1565852-90-5 98%
    ML350 (CYM50202) is a highly potent OPRK1 antagonist with selectivity and broad biological applications. With IC50 values of 9-16 nM, ML350 shows high selectivity for OPRK1, with selectivity of 219-382-fold and 20-35-fold relative to OPRD1 and OPRM1, respectively. ML350 exhibited favorable characteristics in in vivo pharmacokinetic analysis, including high passive membrane permeability and moderate human plasma protein binding. Extensive screening of ML350 against multiple ion channels, receptors, and transporters showed that it does not have adverse off-target effects.
    ML350
  • HY-116167
    RY 024 173990-15-3 98%
    RY 024 is an active compound.
    RY 024
  • HY-116203
    BN 50739 128672-07-1 98%
    BN 50739 is an active compound.
    BN 50739
  • HY-116204
    SKLB70326 1257317-77-3 98%
    SKLB70326 is a small molecule inhibitor of cell cycle progression that induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. SKLB70326 is involved in downregulating cyclin-dependent kinase (CDK) 2, CDK4, and CDK6, while also activating PARP, caspase-3, caspase-9, and Bax, and downregulating Bcl-2.
    SKLB70326
  • HY-116205
    UBP684 1357838-47-1 98%
    UBP684 is a novel positive allosteric modulator of NMDA receptors (NMDARs) that enhances receptor function by stabilizing the ligand-binding domains in a closed conformation, resulting in potentiated whole-cell currents and increased mean open time.
    UBP684
  • HY-116220
    Mcl1-IN-14 2012563-29-8 98%
    Mcl1-IN-14 (compound 5) is a reversible covalent inhibitor of Mcl-1 with the activity of inhibiting Mcl-1. Mcl1-IN-14 covalently targets the non-catalytic lysine side chain of Mcl-1 and has higher potency than non-covalent counterparts, which can be used to develop Mcl-1 inhibitory compounds and study related biological phenomena.
    Mcl1-IN-14
  • HY-116236
    THIIC 1204737-09-6 98%
    THIIC (LY2607540) is a compound with anxiolytic and antidepressant potential. It is a positive allosteric modulator of mGlu receptors, exhibits anxiolytic and antidepressant-like activities in multiple animal models, and can also affect sleep and neurochemical changes.
    THIIC
  • HY-116237
    CREBBP-IN-9 1219576-50-7 98%
    CREBBP-IN-9 (Compound 9) is an inhibitor for CREBBP with an Kd of 29 μM.
    CREBBP-IN-9
  • HY-116238
    ROCK-IN-D2 1219721-78-4 98%
    ROCK-IN-D2 is a potent and selective ROCK inhibitor.
    ROCK-IN-D2
  • HY-116243S
    Vitacoxib-d3
    Vitacoxib-d3 is the deuterium labeled Vitacoxib.
    Vitacoxib-d3
  • HY-116253
    JNJ-42396302 1298030-18-8 98%
    JNJ-42396302 is a PDE10A inhibitor. JNJ-42396302 can be used for the study of infertility.
    JNJ-42396302
  • HY-116254
    L-739750 160141-08-2 98%
    L-739750 is a selective protein farnesyltransferase (PFTase) inhibitor (IC50: 0.4 nM). PFTase utilizes farnesyl diphosphate to farnesylate the cysteine residue of protein substrates having a C-terminal CAAX motif. L-739750 is a selective CAAX peptidomimetic.
    L-739750