Mcl1-IN-14
Mcl1-IN-14 (compound 5) is a reversible covalent inhibitor of Mcl-1 with the activity of inhibiting Mcl-1. Mcl1-IN-14 covalently targets the non-catalytic lysine side chain of Mcl-1 and has higher potency than non-covalent counterparts, which can be used to develop Mcl-1 inhibitory compounds and study related biological phenomena.
For research use only. We do not sell to patients.
- CAS No.: 2012563-29-8
- Formula: C35H32BN3O7
- Molecular Weight:617.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLP-8 | IC50 |
0.46 μM
Compound: 53
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Cytotoxicity against human MOLP8 cells by caspase-3/7 activation
Cytotoxicity against human MOLP8 cells by caspase-3/7 activation
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[PMID: 33333396] |
Chemical Information
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CAS No. 2012563-29-8
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Molecular Weight 617.46
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Formula C35H32BN3O7
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SMILES
O=C(O)C(NC1=C2C=CC=C1C3=C(N(N=C3COC4=CC=C(C(C=O)=C4)B(O)O)C)C)=C2CCCOC5=C6C=CC=CC6=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mcl1-IN-14 Related Classifications
HY-116220 Related Classifications
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