2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. JNJ-42396302

JNJ-42396302 is a PDE10A inhibitor. JNJ-42396302 can be used for the study of infertility.

For research use only. We do not sell to patients.

JNJ-42396302

JNJ-42396302 Chemical Structure

CAS No. : 1298030-18-8

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JNJ-42396302 Related Antibodies

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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Description

JNJ-42396302 is a PDE10A inhibitor. JNJ-42396302 can be used for the study of infertility[1].

IC50 & Target[1]

PDE10A

 

Cellular Effect
Cell Line Type Value Description References
Sf21 IC50
58 nM
Compound: Figure 27, R1C1
Inhibition of rat recombinant PDE10A2 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 60 mins by scintillation proximity assay
Inhibition of rat recombinant PDE10A2 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 60 mins by scintillation proximity assay
[PMID: 22834877]
Clinical Trial
Molecular Weight

353.42

Formula

C19H23N5O2
CAS No.
SMILES

CC1=C(C2=CC=C(CCOC)N=C2)N3N=CC=C(N4CCOCC4)C3=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JNJ-42396302 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-423963021298030-18-8JNJ42396302JNJ 42396302Phosphodiesterase (PDE)PDE10AInhibitorinhibitorinhibit

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