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  3. Drug Derivative
  4. Nav1.7-IN-17

Nav1.7-IN-17 is an active compound.

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Nav1.7-IN-17

Nav1.7-IN-17 Estructura química

No. CAS : 1235403-87-8

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Nav1.7-IN-17 Related Antibodies

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Descripciòn

Nav1.7-IN-17 is an active compound.

Cellular Effect
Cell Line Type Value Description References
HEK293-A IC50
>100000 nM
Compound: I
Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
[PMID: 32392056]
HEK293-A IC50
>100 μM
Compound: I
Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
[PMID: 32392056]
HEK293-A IC50
0.55 nM
Compound: I
Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
[PMID: 32392056]
HEK293-A IC50
1.9 nM
Compound: I
Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
[PMID: 32392056]
HEK293-A IC50
75 μM
Compound: I
Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
[PMID: 32392056]
HEK293-A IC50
75000 nM
Compound: I
Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
[PMID: 32392056]
Peso molecular

538.98

Fòrmula

C21H17ClF2N6O3S2
No. CAS
SMILES

O=S(NC1=NC=NS1)(C2=C(F)C=C(OC3=C(C4=CC=NN4C5CN(C)C5)C=C(Cl)C=C3)C(F)=C2)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Nav1.7-IN-17 Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nav1.7-IN-171235403-87-8Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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Nombre del producto:
Nav1.7-IN-17
Cat. No.:
HY-116137
Cantidad:
MCE Japan Authorized Agent:

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