Nav1.7-IN-17
Nav1.7-IN-17 is an active compound.
For research use only. We do not sell to patients.
- CAS No.: 1235403-87-8
- Formula: C21H17ClF2N6O3S2
- Molecular Weight:538.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293-A | IC50 |
0.55 nM
Compound: I
|
Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
|
[PMID: 32392056] |
| HEK293-A | IC50 |
1.9 nM
Compound: I
|
Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
|
[PMID: 32392056] |
| HEK293-A | IC50 |
>100000 nM
Compound: I
|
Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
|
[PMID: 32392056] |
| HEK293-A | IC50 |
75 μM
Compound: I
|
Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
|
[PMID: 32392056] |
Chemical Information
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CAS No. 1235403-87-8
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Molecular Weight 538.98
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Formula C21H17ClF2N6O3S2
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SMILES
O=S(NC1=NC=NS1)(C2=C(F)C=C(OC3=C(C4=CC=NN4C5CN(C)C5)C=C(Cl)C=C3)C(F)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)