1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-162564
    Antibacterial agent 221
    Inhibitor
    Antibacterial agent 221 (compound 3k) is a potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 221 shows significant cytotoxicity against human LO2 and HepG2 cells.
    Antibacterial agent 221
  • HY-143484
    844-TFM
    Inhibitor
    844-TFM is a NBTI (novel bacterial topoisomerase inhibitor) DNA gyrase inhibitor, with an IC50 of 1.5 μM. 844-TFM exhibits bactericidal properties against M. abscessus.
    844-TFM
  • HY-155510
    DprE1-IN-5
    Inhibitor
    DprE1-IN-5 (Compound 10) is a DprE1 inhibitor. DprE1-IN-5 has anti-TB activity against Mtb H37Rv strain (MIC: 4 μM). DprE1-IN-5 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-5 has high microsomal stability.
    DprE1-IN-5
  • HY-Y0366S4
    Lauric acid-13C-1
    Inhibitor
    Lauric acid-13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-<sup>13</sup>C-1
  • HY-109855
    CP-67015
    Inhibitor
    CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects.
    CP-67015
  • HY-157492
    RO7075573
    Inhibitor
    RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections.
    RO7075573
  • HY-162144
    BDM91288
    Inhibitor
    BDM91288 is an orally active AcrB efflux pump inhibitor of pyridinium piperazine. BDM91288 can enhance the in vivo efficacy of levofloxacin (HY-B0330) in the treatment of Klebsiella pneumoniae pulmonary infection in mouse models.
    BDM91288
  • HY-P5739
    Mram 8
    Inhibitor
    Mram 8 is a cyclotide isolated from Viola philippica, a plant from the Violaceae family.
    Mram 8
  • HY-116479
    Citromycetin
    Inhibitor 99.1%
    Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp.
    Citromycetin
  • HY-119815
    Tenonitrozole
    Inhibitor 99.00%
    Tenonitrozole exhibits antibacterial activity through inhibition of pyruvate-ferredoxin oxidoreductase (PFOR). Tenonitrozole inhibits H. pylori and C. jejuni with MICs of 0.7 μM and 5.9 μM.
    Tenonitrozole
  • HY-P10508
    Pantinin-1
    Inhibitor
    Pantinin-1 is an antimicrobial peptide found in the venom of the Pandinus imperator scorpion. Pantinin-1 has potent antimicrobial activity against Gram-positive bacteria and fungi, weak antimicrobial activity against Gram-negative bacteria, and very low hemolytic activity against human erythrocytes. Pantinin-1 also has anticancer activity and can induce apoptosis in tumor cells.
    Pantinin-1
  • HY-136295
    Quinaldopeptin
    Inhibitor
    Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells.
    Quinaldopeptin
  • HY-119502R
    Camalexin (Standard)
    Inhibitor
    Camalexin (Standard) is the analytical standard of Camalexin. This product is intended for research and analytical applications. Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3].
    Camalexin (Standard)
  • HY-15460R
    CHIR-090 (Standard)
    Inhibitor
    CHIR-090 (Standard) is the analytical standard of CHIR-090. This product is intended for research and analytical applications. CHIR-090 is a potent, slow, tight-binding inhibitor of the LpxC deacetylase. It binds to E. coli LpxC with a Ki of 4.0 nM. CHIR-090 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CHIR-090 (Standard)
  • HY-P11241
    oNCM
    Inhibitor
    oNCM is an antibacterial peptide. oNCM has good antibacterial activity, anti biofilm ability, anti-inflammatory effect, high stability, and low cytotoxicity. oNCM can be used for research on infectious or inflammatory conditions.
    oNCM
  • HY-100381R
    Nigericin sodium salt (Standard)
    Inhibitor
    Nigericin (sodium salt) (Standard) is the analytical standard of Nigericin (sodium salt). This product is intended for research and analytical applications. Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1/GSDMD in TNBC.
    Nigericin sodium salt (Standard)
  • HY-P5731
    Bac7(1-35)
    Inhibitor
    Bac7(1-35) is a proline-rich antimicrobial peptide. Bac7(1-35) efficiently binds to different regions of prokaryote ribosomes, leading to the inhibition of protein synthesis. Bac7(1-35) demonstrates in vitro activity against P. aeruginosa strains.
    Bac7(1-35)
  • HY-161823
    Anti-MRSA agent 13
    Inhibitor
    Anti-MRSA agent 13 (Compound 9b) is an agent against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.5–2 μg/mL against clinically isolated MRSA strains. Anti-MRSA agent 13 possesses favorable biosafety, plasma tolerance stability, and a low tendency to develop resistance. Anti-MRSA agent 13 disrupts cell walls and membranes, reduces metabolic activity, causes oxidative damage, affects DNA function, and ultimately leads to MRSA death through multi-target synergies.
    Anti-MRSA agent 13
  • HY-P5256
    Oligopeptide-20
    Inhibitor
    Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient.
    Oligopeptide-20
  • HY-P2483
    Octaarginine
    Inhibitor
    Octaarginine is a cell-penetrating peptide and proteasome inhibitor. Octaarginine exhibits mixed-type inhibition against 20S proteasome chymotrypsin-like, caspase-like, and trypsin-like activities, and inhibits 26S proteasome activity with decreased efficiency. Octaarginine induces ubiquitin-conjugated protein accumulation, mediates HSPG-dependent cellular internalization via macropinocytosis, enhances liposomal cargo uptake and gene delivery. Octaarginine can be used for the research of cervix carcinoma, collagen antibody-induced arthritis, and bacterial infections.
    Octaarginine
Cat. No. Product Name / Synonyms Application Reactivity