1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-158272
    Penicillin/OVA
    Inhibitor
    Penicillin/OVA is a conjugate of penicillin and Ovalbumins, that is utilized as an antigen in immunological research. Penicillin/OVA causes IgE-dependent anaphylactic response to penicillin in mice.
    Penicillin/OVA
  • HY-N6687A
    Calcimycin hemicalcium salt
    Inhibitor
    Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium salt induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium salt inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium salt also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium salt induces apoptosis and autophagy.
    Calcimycin hemicalcium salt
  • HY-177852
    Anthranilyl-AMSN
    Anthranilyl-AMSN is a potent PqsA inhibitor, with a Kiapp of 170 nM. Anthranilyl-AMSN decreases HHQ and PQS production. Anthranilyl-AMSN can be used in the research of Pseudomonas aeruginosa infections.
    Anthranilyl-AMSN
  • HY-P10513
    AcrAP1
    Inhibitor
    AcrAP1 (AP1-Z1) is an antimicrobial peptide found in the venom of the Arabian scorpion (Androctonus crassicauda). AcrAP1 has antimicrobial activity and can inhibit the growth of Gram-positive and Gram-negative bacteria as well as yeast. AcrAP1 exerts antitumor activity by promoting apoptosis of cancer cells and inhibiting angiogenesis. AcrAP1 can be used in cancer therapy research.
    AcrAP1
  • HY-P11468
    wkwkwNGwkwkw-NH2
    Inhibitor
    wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing.
    wkwkwNGwkwkw-NH2
  • HY-136887
    Arphamenine B hemisulfate
    Inhibitor
    Arphamenine B hemisulfate is a Zn2+-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B hemisulfate is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B hemisulfate enhances the immune response and is used to characterize novel proteases.
    Arphamenine B hemisulfate
  • HY-105523
    S 3578 sulfate
    Inhibitor
    S 3578 sulfate is a broad-spectrum antibacterial agent, particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) (MIC = 0.78-3.13 μg/mL) and Pseudomonas aeruginosa (MIC = 1.56-6.25 μg/mL). S 3578 sulfate can be used in the research of infectious conditions.
    S 3578 sulfate
  • HY-155644
    ROS inducer 1
    Inhibitor
    ROS inducer 1 (compound I29) is a fungicide, with EC50 against Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo), and Pseudomonas syringae pv. actinidiae (Psa) of 5.73, 6.62 and 9.05 μg/mL. ROS inducer 1 can effectively induce the production of ROS in Xanthomonas cells and inhibit rice bacterial blight. ROS inducer 1 has the potential to study bacterial infection in crops.
    ROS inducer 1
  • HY-W721828
    2-Thiophenecarboxaldehyde-d3
    2-Thiophenecarboxaldehyde-d3 (Thiophene-2-carboxaldehyde-d3) is the deuterium labeled 2-Thiophenecarboxaldehyde (HY-W012941). 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities.
    2-Thiophenecarboxaldehyde-d<sub>3</sub>
  • HY-129728
    Lienomycin
    Inhibitor
    Lienomycin, a polyene antibiotic produced by Actinomyces distatochromogenes var. lienomycini, exhibits antifungal, antibacterial and antitumor activity.
    Lienomycin
  • HY-P5577
    Aurein 5.2
    Inhibitor
    Aurein 5.2 is an antibiotic antimicrobial peptide.
    Aurein 5.2
  • HY-W013186S
    Lansoprazole sulfide-d4
    Inhibitor 99.0%
    Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.
    Lansoprazole sulfide-d<sub>4</sub>
  • HY-W354203
    N'-Isonicotinoylisonicotinohydrazide
    Inhibitor
    N'-Isonicotinoylisonicotinohydrazide (Compound 7, 1,2-Diisonicotinoylhydrazine) is a competitive inhibitor (IC50=5-30 μM) of bacterial heme oxygenase (HO). N'-Isonicotinoylisonicotinohydrazide inhibits iron release and bacterial iron acquisition. N'-Isonicotinoylisonicotinohydrazide exhibits selective activity against HO enzymes from Pseudomonas aeruginosa and Neisseria meningitidis. N'-Isonicotinoylisonicotinohydrazide is promising for research of multidrug-resistant Gram-negative bacterial infections.
    N'-Isonicotinoylisonicotinohydrazide
  • HY-N18777
    Moringa oleifera extract
    Moringa oleifera extract contains a variety of active ingredients, including vitamins (A, C, E and various B vitamins), minerals (calcium, iron, potassium, magnesium), flavonoids, phenolic acids and alkaloids, which have antioxidant, anti-inflammatory, antibacterial and antiviral properties.
    Moringa oleifera extract
  • HY-N9531
    3'-Hydroxyxanthyletin
    Inhibitor
    3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities.
    3'-Hydroxyxanthyletin
  • HY-172895
    Quorum sensing-IN-10
    Inhibitor
    Quorum sensing-IN-10 (10p), an antibacterial synergist, shows significant inhibition of P. aeruginosa virulence, biofilm, and motility, with low toxicity. Quorum sensing-IN-10 (10p) can be used in the research for drug-resistant Pseudomonas aeruginosa infections.
    Quorum sensing-IN-10
  • HY-N18757
    Tinospora cordifolia extract
    Tinospora Cordifolia Extract is rich in bioactive compounds-such as alkaloids, glycosides, polysaccharides, and lignans—and possesses immunomodulatory, anti-inflammatory, antioxidant, and antimicrobial activities.
    Tinospora cordifolia extract
  • HY-132923
    NBTIs-IN-4
    Inhibitor
    NBTIs-IN-4 demonstrates potent antibacterial activity against diverse Gram-positive pathogens, inhibition of both DNA gyrase and topoisomerase IV, a low frequency of resistance.
    NBTIs-IN-4
  • HY-13451A
    Finafloxacin hydrochloride
    Inhibitor
    Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments.
    Finafloxacin hydrochloride
  • HY-N14781
    10-Decarbamoyloxy-9-dehydromitomycin B
    Inhibitor
    10-Decarbamoyloxy-9-dehydromitomycin B is a mitomycin. 10-Decarbamoyloxy-9-dehydromitomycin B has antibacterial and antitumor activity.
    10-Decarbamoyloxy-9-dehydromitomycin B
Cat. No. Product Name / Synonyms Application Reactivity