wkwkwNGwkwkw-NH2 

wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing^[1].

1818.13

C₉₆H₁₂₀N₂₄O₁₃

{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-Asn-Gly-{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-NH2

{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-NG-{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Li B, et al. Novel β-Hairpin Antimicrobial Peptide Containing the β-Turn Sequence of -NG- and the Tryptophan Zippers Facilitate Self-Assembly into Nanofibers, Exhibiting Excellent Antimicrobial Performance. J Med Chem. 2024 Apr 25;67(8):6365-6383.  [Content Brief]