1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. Calcium Channel
  4. Calcium Channel Isoform
  5. Calcium Channel Inhibitor

Calcium Channel Inhibitor

Calcium Channel Inhibitors (183):

Cat. No. Product Name Effect Purity
  • HY-13433
    Thapsigargin
    Inhibitor 99.95%
    Thapsigargin, an endoplasmic reticulum (ER) stress inducer, is an inhibitor of microsomal Ca2+-ATPase.
  • HY-W009724
    2-Aminoethyl diphenylborinate
    Inhibitor 98.36%
    2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R.
  • HY-10805
    Almorexant
    Inhibitor 99.71%
    Almorexant (ACT 078573) is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively.
  • HY-13750
    Ebselen
    Inhibitor 99.58%
    Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker.
  • HY-N1584
    Halofuginone
    Inhibitor 99.78%
    Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM.
  • HY-13764
    Tetrandrine
    Inhibitor 99.90%
    Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
  • HY-131614
    TPC2-A1-N
    Inhibitor 99.90%
    TPC2-A1-N is a powerful and Ca2+-permeable agonist of two pore channel 2 (TPC2), which plays its role by mimicking the physiological actions of NAADP.
  • HY-A0057
    Gabapentin
    Inhibitor ≥98.0%
    Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker.
  • HY-15553A
    Mibefradil dihydrochloride
    Inhibitor 98.78%
    Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively).
  • HY-B0309
    Felodipine
    Inhibitor 99.35%
    Felodipine, a dihydropyridine, is a potent, vasoselective calcium channel antagonist.
  • HY-12507
    GSK-7975A
    Inhibitor 99.79%
    GSK-7975A is a potent and orally available CRAC channel inhibitor.
  • HY-B0265
    Nimodipine
    Inhibitor 99.76%
    Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist.
  • HY-17401
    Ranolazine dihydrochloride
    Inhibitor 99.79%
    Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP).
  • HY-N1584A
    Halofuginone hydrobromide
    Inhibitor 99.55%
    Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM.
  • HY-B0280
    Ranolazine
    Inhibitor 99.72%
    Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP).
  • HY-12515A
    Nicardipine hydrochloride
    Inhibitor 99.80%
    Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels.
  • HY-12542A
    Dantrolene sodium hemiheptahydrate
    Inhibitor ≥98.0%
    Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
  • HY-101379A
    8-Bromo-cGMP sodium
    Inhibitor 99.07%
    8-Bromo-cGMP sodium, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator.
  • HY-103316
    trans-Ned 19
    Inhibitor 99.53%
    trans-Ned 19, a NAADP antagonist and TPC blocker, suppresses the calcium signal in human umbilical vein endothelial cells (HUVEC) and the rat aorta relaxation in response to low histamine concentrations.
  • HY-B0122
    Topiramate
    Inhibitor ≥98.0%
    Topiramate (McN 4853) is a broad-spectrum antiepileptic agent.