1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-123474
    PF-1163B
    PF-1163B is an antifungal antibiotic.
    PF-1163B
  • HY-164643
    Antifungal agent 113
    Antifungal agent 113 (compound 9a) is a potent antifungal and antibacterial agent. Antifungal agent 113 shows good antibacterial activity against S. aureus and methicillin-resistant S. aureus.
    Antifungal agent 113
  • HY-155167
    Anticancer agent 151
    Anticancer agent 151 (compound 6C) is an anticancer agent. Anticancer agent 151 exhibits excellent in vitro cytotoxic activity against MCF-7 cells with an IC50 value of 6.3 μM.
    Anticancer agent 151
  • HY-N14305
    44-Homooligomycin B
    44-HomooIigomycin B is an antitumor antibiotic. 44-Homooligomycin B has activity against fungi such as Aspergillus, Penicillium and Fusarium, but not against yeast and bacteria. 44-Homooligomycin B has moderate anti-tumor activity against Colon 26 in vivo.
    44-Homooligomycin B
  • HY-24470B
    1-(9H-Fluoren-9-yl)ethanol
    1-(9H-Fluoren-9-yl)ethanol is a prominent fragment in β-lactam antibiotic modification and an important building block for anti-inflammatory agent.
    1-(9H-Fluoren-9-yl)ethanol
  • HY-116571
    RU44790
    RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative bacteria and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research.
    RU44790
  • HY-W088872S
    (R)-2-Methylbutanoic acid-d3
    (R)-2-Methylbutanoic acid-d3 is the deuterium labeled (R)-2-Methylbutanoic acid.
    (R)-2-Methylbutanoic acid-d<sub>3</sub>
  • HY-N14491
    Coumamidine γ2
    Coumamidine γ2 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa.
    Coumamidine γ2
  • HY-A0256BR
    Clavulanate lithium (Standard)
    Clavulanate (lithium) (Standard) is the analytical standard of Clavulanate (lithium). This product is intended for research and analytical applications. Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic.
    Clavulanate lithium (Standard)
  • HY-121395
    Lepiochlorin
    Lepiochlorin is an antibiotic metabolite produced by a fungus (Lepiota species) that is cultivated by ants, which can prevent fungal contamination.
    Lepiochlorin
  • HY-N14216
    Polyoxin L
    Polyoxin L is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight.
    Polyoxin L
  • HY-B1366R
    Meclocycline Sulfosalicylate Salt (Standard)
    Meclocycline (Sulfosalicylate Salt) (Standard) is the analytical standard of Meclocycline (Sulfosalicylate Salt). This product is intended for research and analytical applications. Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris.
    Meclocycline Sulfosalicylate Salt (Standard)
  • HY-B0330BS1
    Levofloxacin-d3 hydrochloride
    Levofloxacin-d3 ((-)-Ofloxacin-d3) hydrochlorideis deuterium labeled Levofloxacin (hydrochloride). Levofloxacin ((-)-Ofloxacin) hydrochloride is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrochloride can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrochloride shows anti-orthopoxvirus activity.
    Levofloxacin-d<sub>3</sub> hydrochloride
  • HY-163915
    8-(4-(Trifluoromethyl)anilino)quercetin
    8-(4-(Trifluoromethyl)anilino)quercetin is a potent ErmA inhibitor. 8-(4-(Trifluoromethyl)anilino)quercetin has antioxidant and anti-inflammatory activity.
    8-(4-(Trifluoromethyl)anilino)quercetin
  • HY-126170
    Valanimycin
    Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC50 of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice.
    Valanimycin
  • HY-105751
    Kalafungin
    Kalafungin is an antibiotic, antimicrobial agent and a β-lactamase inhibitor from marine Streptomyces, with IC50 of 225.37 μM. Kalafungin destroys cell membranes. Kalafungin shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria (such as S. aureus ATCC 33591 and S. aureus ATCC 23591), and, to a lesser extent, gram-negative bacteria.
    Kalafungin
  • HY-N15420
    Leucomycin A7
    Leucomycin A7 is a member of the leucomycin complex that can be isolated from Streptomyces kitasatoensis. Leucomycin A7 has antibacterial activity and has strong inhibitory effects on the growth of Gram-positive bacteria, but weak inhibitory effects on Gram-negative bacteria.
    Leucomycin A7
  • HY-N15107
    Polyoxin M
    Polyoxin M is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight.
    Polyoxin M
  • HY-N14802
    Napyradiomycin B1
    Napyradiomycin B1 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B1 almost none to Gram-negative bacteria and fungi. IC50 (μg/mL) of leukemia L-1210 cells is 2.2.
    Napyradiomycin B1
  • HY-119839
    Acediasulfone
    Acediasulfone is an antimicrobial. Acediasulfone can formation of a colored product reaction with p-dimethylaminobenzaldehyde.
    Acediasulfone

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