Anticancer agent 151
Anticancer agent 151 (compound 6C) is an anticancer agent. Anticancer agent 151 exhibits excellent in vitro cytotoxic activity against MCF-7 cells with an IC50 value of 6.3 μM.
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- CAS No.: 1227476-97-2
- 화학식: C22H18Cl2N2O3
- 분자량:429.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
>10 μM
Compound: 6c
|
Cytotoxicity against human K562 cells after 72 hrs by calcein-AM assay
Cytotoxicity against human K562 cells after 72 hrs by calcein-AM assay
|
[PMID: 23981532] |
| MCF7 | IC50 |
7.9 μM
Compound: 6c
|
Cytotoxicity against human MCF7 cells after 72 hrs by calcein-AM assay
Cytotoxicity against human MCF7 cells after 72 hrs by calcein-AM assay
|
[PMID: 23981532] |
Chemical Information
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CAS No. 1227476-97-2
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분자량 429.30
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화학식 C22H18Cl2N2O3
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SMILES
O=C(C1=C(C=CC(Cl)=C1)O)N[C@H](C(NC2=CC=C(C=C2)Cl)=O)CC3=CC=CC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Imramovský A, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines. Eur J Med Chem. 2013;68:253-259. [Content Brief]
[2]. Aleš Imramovský, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines. Eur J Med Chem. 2013. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)