2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3836):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W105739
    18-Hydroxyoctadecanoic acid
    		99.69%
    18-Hydroxyoctadecanoic acid (Octadecanoic acid, 18-hydroxy) is an ester product.
    18-Hydroxyoctadecanoic acid
  • HY-W670044
    9-Oxooctadecanoic acid
    9-Oxooctadecanoic acid (9-Oxostearic acid; 9-Ketostearic acid) is an ester product.
    9-Oxooctadecanoic acid
  • HY-77732
    Ticagrelor acetonide
    		98.65%
    Ticagrelor acetonide (Isopropylidene ticagrelor) (Compound 7) is a drug intermediate that can be used for the synthesis of lysine-specific demethylase (LSD1) inhibitors.
    Ticagrelor acetonide
  • HY-P4047
    Cyclo(RGDfK(Mal))
    		99.30%
    Cyclo(RGDfK(Mal)) is a pentapeptide. Cyclo(RGDfK(Mal)) improves the attachment and infiltration of human pluripotent stem cells. Cyclo(RGDfK(Mal)) can be used for 3D stem cell culture and expansion.
    Cyclo(RGDfK(Mal))
  • HY-N10478A
    Sitosterol sulfate trimethylamine
    Sitosterol sulfate (trimethylamine) is an active compound. Sitosterol sulfate can be used in a variety of biological research.
    Sitosterol sulfate trimethylamine
  • HY-107944
    Chlorphenesin carbamate
    		99.12%
    Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133). Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels. Antinociceptive effect.
    Chlorphenesin carbamate
  • HY-76633
    Dimethyl 4-hydroxyisophthalate
    		99.66%
    Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue.
    Dimethyl 4-hydroxyisophthalate
  • HY-164165
    Paclitaxel-2′-succinate NHS ester
    		98.78%
    Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy.
    Paclitaxel-2′-succinate NHS ester
  • HY-B0910A
    Pyrithioxin dihydrochloride
    		98.0%
    Pyrithioxin (Pyritinol) dihydrochloride is the dihydrochloride salt of Pyrithioxin (HY-B0910). Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis.
    Pyrithioxin dihydrochloride
  • HY-111013
    VK-II-86
    VK-II-86 is a Carvedilol (HY-B0006) analogue lacking antagonist activity at β-adrenoceptors, in hypokalaemia. VK-II-86 prevents hypokalaemia-induced ventricular arrhythmia through multi-channel effects. VK-II-86 prevents all hypokalaemia-induced changes in ion channel activity and oxidative stress.
    VK-II-86
  • HY-153606
    VUBI1 analogue-1
    		98.94%
    VUBI1 analogue-1 (compound 79) is a VUBI1 (HY-111671) analogue. VUBI1 (SOS1 activator 1) is a SOS1 activator with a Kd of 44 nM. VUBI1 analogue-1 can be used to synthesize (4S)-PROTAC SOS1 degrader-1 (HY-144657)[1].
    VUBI1 analogue-1
  • HY-W031510
    3,6-Dihydroxyxanthone
    		99.55%
    3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research.
    3,6-Dihydroxyxanthone
  • HY-120784
    Hexafluoro-diallylhexaflurobisphenol
    		99.79%
    Hexafluoro-diallylhexaflurobisphenol is a Honokiol analogue (HA). Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules.
    Hexafluoro-diallylhexaflurobisphenol
  • HY-124108
    Eicosatetraynoic acid
    		99.9%
    Eicosatetraynoic acid (ETYA) is a non-metabolizable analog of Arachidonic acid (HY-109590) and also an inhibitor of the lipoxygenase (LOX)/cyclooxygenase (COX) pathway (ID50 = 8 μM and 4 μM). Eicosatetraynoic acid acts as a suicide substrate to inhibit the production of inflammatory mediators such as leukotrienes and prostaglandins. Eicosatetraynoic acid acts directly on cell membranes and membrane proteins to exert a wide range of effects, including blocking potassium channels, increasing cell membrane fluidity, elevating intracellular calcium levels, inhibiting DNA synthesis in tumor cells, inducing differentiation of certain cells, and specifically inhibiting the assembly and replication of orthopoxviruses. Eicosatetraynoic acid alleviates acute lung injury induced by chemicals such as phosgene.
    Eicosatetraynoic acid
  • HY-153128
    DOCK2-IN-1
    		99.37%
    DOCK2-IN-1 (Compound 3) is an analog of CPYPP (HY-110100) and a DOCK2 inhibitor (IC50 = 19.1 μM). DOCK2-IN-1 binds to the DHR-2 domain of DOCK2 and inhibits its mediated Rac guanine nucleotide exchange factor activity. DOCK2-IN-1 blocks chemokine receptor- and antigen receptor-mediated activation of Rac in lymphocytes. DOCK2-IN-1 significantly inhibits chemotaxis and T cell activation. DOCK2-IN-1 can be used in the research of transplant rejection and organ-specific autoimmune diseases.
    DOCK2-IN-1
  • HY-16394
    PG-11047 tetrahydrochloride
    		99.59%
    PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities.
    PG-11047 tetrahydrochloride
  • HY-W701069
    Isomyosmine
    Isomyosmine is a nitrate reductase inhibitor. Isomyosmine is a nicotine related alkaloid present in solanecea plants containing nicotine. Isomyosmine can be used for research of inflammation and age-related disorders
    Isomyosmine
  • HY-W017764
    7,8-Dihydro-2,5(1H,6H)-quinolinedione
    		99.86%
    7,8-Dihydro-2,5(1H,6H)-quinolinedione (compound SF32) is a positive inotropic agent.
    7,8-Dihydro-2,5(1H,6H)-quinolinedione
  • HY-W130397
    (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-oxo-4-(tritylamino)butanoic acid
    		99.45%
    (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-oxo-4-(tritylamino)butanoic acid is an asparagine derivative.
    (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-oxo-4-(tritylamino)butanoic acid
  • HY-141630
    Sphingosine-1-phosphate (d17:1)
    		99.00%
    Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer.
    Sphingosine-1-phosphate (d17:1)