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    Cell Cycle/DNA Damage
  2. COX
    PPAR
  3. Eicosatetraynoic acid

Eicosatetraynoic acid (Synonyms: ETYA)

Cat. No.: HY-124108
Handling Instructions

Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM.

For research use only. We do not sell to patients.

Eicosatetraynoic acid Chemical Structure

Eicosatetraynoic acid Chemical Structure

CAS No. : 1191-85-1

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1 mg USD 95 In-stock
Estimated Time of Arrival: December 31
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Description

Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively)[1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM[2].

IC50 & Target[2]

COX

8 μM (ID50)

Molecular Weight

296.40

Formula

C₂₀H₂₄O₂

CAS No.

1191-85-1

SMILES

CCCCCC#CCC#CCC#CCC#CCCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (6.75 mM; Need ultrasonic)

Ethanol : < 1 mg/mL (insoluble)

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3738 mL 16.8691 mL 33.7382 mL
5 mM 0.6748 mL 3.3738 mL 6.7476 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
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Eicosatetraynoic acid
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