Pyrithioxin dihydrochloride (Synonyms: Pyritinol dihydrochloride; Pyridoxine disulfide dihydrochloride; Vitamin B6 disulfide dihydrochloride)

Cat. No.: HY-B0910A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

For research use only. We do not sell to patients.

Pyrithioxin dihydrochloride Chemical Structure

CAS No. : 10049-83-9

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in Water ready for reconstitution	USD 66	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 66	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Other Forms of Pyrithioxin dihydrochloride:

Pyrithioxin Get quote

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Description

Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

IC₅₀ & Target

Human Endogenous Metabolite

Clinical Trial

Molecular Weight

441.39

Appearance

Solid

Formula

C₁₆H₂₂Cl₂N₂O₄S₂

CAS No.

10049-83-9

SMILES

OCC1=C(CSSCC2=C(CO)C(O)=C(C)N=C2)C=NC(C)=C1O.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 66.67 mg/mL (151.05 mM; Need ultrasonic)

H₂O : 50 mg/mL (113.28 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2656 mL	11.3279 mL	22.6557 mL
5 mM	0.4531 mL	2.2656 mL	4.5311 mL
10 mM	0.2266 mL	1.1328 mL	2.2656 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: PBS
Solubility: 11.11 mg/mL (25.17 mM); Clear solution; Need ultrasonic and adjust pH to 1 with 1M HCl

*All of the co-solvents are available by MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (252 KB) HNMR (253 KB)

Handling Instructions (2659 KB)

References

[1]. Stoica E, et al. Facilitation through hyperventilation of therapeutic effect of pyrithioxin in cerebral infarct patients. Eur Neurol. 1975;13(4):285-303. [Content Brief]

Pyrithioxin dihydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

Pyrithioxin10049-83-9PyritinolPyridoxine disulfideVitamin B6 disulfideEndogenous MetaboliteInhibitorinhibitorinhibit

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