Pyrithioxin dihydrochloride (Standard)
Pyrithioxin (Pyritinol) dihydrochloride (Standard) is the analytical standard of Pyrithioxin dihydrochloride (HY-B0910A). Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis.
For research use only. We do not sell to patients.
- Purity: 95%
- CAS No.: 10049-83-9
- Formula: C16H22Cl2N2O4S2
- Molecular Weight:441.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 10049-83-9
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Molecular Weight 441.39
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Formula C16H22Cl2N2O4S2
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SMILES
OCC1=C(CSSCC2=C(CO)C(O)=C(C)N=C2)C=NC(C)=C1O.[H]Cl.[H]Cl
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Synonyms
Pyritinol dihydrochloride (Standard); Pyridoxine disulfide dihydrochloride (Standard); Vitamin B6 disulfide dihydrochloride (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Stoica E, et al. Facilitation through hyperventilation of therapeutic effect of pyrithioxin in cerebral infarct patients. Eur Neurol. 1975;13(4):285-303. [Content Brief]
[2]. von Metzler A. et al. [Antineoplastic activity of drugs affecting the central nervous system against chemically induced tumors in the rat (author's transl)]. J Cancer Res Clin Oncol. 1979 Sep;95(1):11-8. German. [Content Brief]
[3]. Crouzet J, et al. Pyrithioxine et polyarthrite rhumatoïde [Pyrithioxin and rheumatoid polyarthritis]. Rev Rhum Mal Osteoartic. 1986 Jan;53(1):45-8. [Content Brief]
[4]. Marston HM, et al. Effects of the chronic administration of pyrithioxin on behaviour and cholinergic function in young and aged rats. J Psychopharmacol. 1987 Jan;1(4):237-43. [Content Brief]
[5]. Zheng S, et al. Combined mutagenesis and metabolic regulation to enhance D-arabitol production from Candida parapsilosis. J Ind Microbiol Biotechnol. 2020 May;47(4-5):425-435. [Content Brief]
[6]. Martínez-Lage JM, et al. Asociación de piritioxina y difenilhidantoina, en el tratamiento de los síndromes epilépticos orgánicos [Association of pyrithioxin and diphenylhydantoin in the treatment of organic epileptic syndromes]. Med Clin (Barc). 1965 Sep;45(3):204-5. [Content Brief]
[7]. Jiménez-Andrade GY, et al. Pyritinol reduces nociception and oxidative stress in diabetic rats. Eur J Pharmacol. 2008 Aug 20;590(1-3):170-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Pyrithioxin dihydrochloride (Standard)
- 10049-83-9
- Pyritinol dihydrochloride (Standard)
- Pyridoxine disulfide dihydrochloride (Standard)
- Vitamin B6 disulfide dihydrochloride (Standard)
- Reference Standards
- Drug Derivative
- Glucose
- Amino acids
- Cerebral infarct
- Epilepsy
- Fibrosarcomas
- Rheumatoid polyarthritis
- D-arabitol
- Candida parapsilosis
- 3-MC
- Acetylcholine
- Inhibitor
- inhibitor
- inhibit