Thrombin (MW 37kDa)

Cat. No.: HY-114164: Data Sheet
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Thrombin (MW 37kDa) is a Na⁺-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.

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CAS No. : 9002-04-4

사이즈	가격	재고	수량
1000 U		해외재고보유	Estimated Time of Arrival: December 31
2000 U		해외재고보유	Estimated Time of Arrival: December 31

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고객리뷰

Based on 7 publication(s) in Google Scholar

Other Forms of Thrombin (MW 37kDa):

Thrombin, Pig blood In-stock
Rat Thrombin In-stock
Human α-Thrombin (Lyophilized) In-stock
Murine Thrombin In-stock
Rabbit Thrombin 견적 받기
Canine Thrombin 견적 받기

7 Publications Citing Use of MCE Thrombin (MW 37kDa)

•bioRxiv. 2026 Mar 5:2026.03.03.709348.

Flow Cytometry

Cell Imaging/Staining

ELISA

Cell Migration/Invasion Assay

: Thrombin (MW 37kDa) purchased from MedChemExpress. Usage Cited in: Cancer Commun (Lond). 2025 Feb;45(2):143-166. [Abstract]; Platelets were treated with Fc fragment, Thrombin (1 µg/mL; 2 h), EphB1‐Fc, Thrombin + EphB1‐Fc, mono EphB1, mono EphB1 + EphB1‐Fc, or EFNB1 Ab + EphB1‐Fc. Platelets without treatment served as controls. CD62P expression in activated platelets was tested by flow cytometry analysis. Representative flow cytometry analysis of CD62P expression is presented on the left. The right graph shows the percentage of CD62P+ platelets. Data were presented as the means ± SD, with n = 3 per group.

: Thrombin (MW 37kDa) purchased from MedChemExpress. Usage Cited in: Mol Carcinog. 2024 Jul;63(7):1288-1302. [Abstract]; Effect of knockdown of KDM4E and combined overexpression of BICD1 on the proliferative activity of Thrombin (1 pM)-activated TNBC cells detected by EdU staining (scale bar: 50 μm).

: Thrombin (MW 37kDa) purchased from MedChemExpress. Usage Cited in: Mol Carcinog. 2024 Jul;63(7):1288-1302. [Abstract]; Effect of knockdown of KDM4E and combined overexpression of BICD1 on the invasive activity of Thrombin (1 pM)-activated TNBC cells detected by Transwell assay (scale bar: 50 μm). *p < 0.05 versus the sh-scramble group, #p < 0.05 versus the sh-KDM4E + oe-NC group, &p < 0.05 versus the blank group.

: Thrombin (MW 37kDa) purchased from MedChemExpress. Usage Cited in: Allergy. 2022 Jul;77(7):2104-2120. [Abstract]; Western blots for the HA tag on RRL-expressed IL-33 showing the Thrombin cleavage of human pro-IL-33 into the two main forms, ~18 and ~25 kDa, and the inhibition of these cleavage events by the Thrombin inhibitor Argatroban (50 μg/ml). Cleavage occurred in a time-dependent manner (15 min, 30 min, 1 h, 2 h and 4 h; 0.075 U Thrombin; 15 μL buffer) (A) and a dose-dependent manner (0.01875, 0.0375, 0.075, 0.15 and 0.3 U; RT for 1 h; 15 μL buffer) (B).

: Thrombin (MW 37kDa) purchased from MedChemExpress. Usage Cited in: Allergy. 2022 Jul;77(7):2104-2120. [Abstract]; L-33-dependent IL-5, IL-13 and IL-4 production by ST2+ CD4 cells incubated with or without Thrombin (50 pg RRL; 0.075 U Thrombin; RT for 1 h) and with or without a neutralizing hIL-33 mAb. The bars and error bars represent the mean ± SEM; *p < .05; **p < .01; ***p < .001.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명	Thrombin (MW 37kDa) is a Na⁺-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.
In Vitro	p62 is cleaved from the agarose beads as well as the GST tag by addition of Thrombin (1 Unit/100 μg protein) at room temperature for 20 h^[3]. Thrombin solution: Dissolve in PBS prechilled to 4°C. Swirl gently. Store solution in small aliquots at -80°C to preserve activity. Cleavage buffer: PBS (140 mM NaCl, 2.7 mM KCl, 10 mM Na₂HPO₄, 1.8 mM KH₂PO₄) pH 7.3. Elution buffer: 50 mM Tris-HCl, 10 mM reduced glutathione, pH 8.0 MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Thrombin (MW 37kDa) Related Antibodies
분자량	37000(Average)
CAS No.	9002-04-4
Appearance	Solid
Color	White to off-white
SMILES	[Thrombin (MW 37kDa)]
선적	Room temperature in continental US; may vary elsewhere.
보관	Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서	Select Batch: Data Sheet (269 KB) SDS (419 KB) COA (242 KB) Handling Instructions (2659 KB)
References	[1]. Golderman V, et al. Thrombin and the Protease-Activated Receptor-1 in Organophosphate-Induced Status Epilepticus. J Mol Neurosci. 2018 Dec 4. [Content Brief] [2]. Krenzlin H, et al. The Importance of Thrombin in Cerebral Injury and Disease. Int J Mol Sci. 2016 Jan 11;17(1). [Content Brief] [3]. Geetha T, et al. p62 serves as a shuttling factor for TrkA interaction with the proteasome. Biochem Biophys Res Commun. 2008 Sep 12;374(1):33-7. [Content Brief]

Thrombin (MW 37kDa) Related Classifications

Neurological Disease

몰농도 계산기
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thrombin (MW 37kDa)9002-04-4ThrombinInhibitorinhibitorinhibit

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Thrombin (MW 37kDa)

고객리뷰

Other Forms of Thrombin (MW 37kDa):

Thrombin (MW 37kDa) Related Antibodies

7 Publications Citing Use of MCE Thrombin (MW 37kDa)

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

고객리뷰

Thrombin (MW 37kDa) Related Antibodies

Thrombin (MW 37kDa) Related Classifications

몰농도 계산기

농도 희석 계산기

The molarity calculator equation

The dilution calculator equation

Keywords:

최근 본 상품:

고객리뷰

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