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  3. Etomoxir sodium salt

Etomoxir sodium salt (Synonyms: (R)-(+)-Etomoxir sodium salt)

Cat. No.: HY-50202A Purity: 99.15%
Handling Instructions

Etomoxir sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

For research use only. We do not sell to patients.

Etomoxir sodium salt Chemical Structure

Etomoxir sodium salt Chemical Structure

CAS No. : 828934-41-4

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10 mM * 1 mL in Water USD 92 In-stock
Estimated Time of Arrival: December 31
5 mg USD 84 In-stock
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10 mg USD 144 In-stock
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50 mg USD 504 In-stock
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Customer Review

Based on 10 publication(s) in Google Scholar

Other Forms of Etomoxir sodium salt:

Top Publications Citing Use of Products

    Etomoxir sodium salt purchased from MCE. Usage Cited in: Oncotarget. 2016 Oct 11;7(41):67071-67086.

    MDA-MB-453 cells are treated as indicated for 2 days and subjected to immunoblotting. Combination treatments using non-saturating doses of Etomoxir and MTI-31 or Rapamycin results in an enhanced growth suppression in MDA-MB-453 cells, which is not readily observed in MDA-MB-231 cells, correlating a nearly complete suppression of cyclin D1 and c-Myc level in MDA-MB-453 cells under the combination treatments.
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    Description

    Etomoxir sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

    IC50 & Target

    CPT-1a[2]

    Molecular Weight

    320.74

    Formula

    C₁₅H₁₈ClNaO₄

    CAS No.

    828934-41-4

    SMILES

    ClC1=CC=C(OCCCCCC[[email protected]@]2(CO2)C([O-])=O)C=C1.[Na+]

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    4°C, stored under nitrogen

    *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

    Solvent & Solubility
    In Vitro: 

    H2O : 80 mg/mL (249.42 mM; Need warming)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.1178 mL 15.5890 mL 31.1779 mL
    5 mM 0.6236 mL 3.1178 mL 6.2356 mL
    10 mM 0.3118 mL 1.5589 mL 3.1178 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References

    Purity: 99.15%

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    Product name:
    Etomoxir sodium salt
    Cat. No.:
    HY-50202A
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