2. Immunology/Inflammation
  3. Interleukin Related
  4. Abrezekimab

Abrezekimab  (Synonyms: UCB4144; VR 942)

製品番号: HY-P99417 純度: 95.00%
COA Technical Support

Abrezekimab (UCB4144; VR 942) is a humanized, high-affinity, neutralizing anti-human-IL-13 antibody fragment that binds to IL-13. Abrezekimab prevents IL-13 binding to the IL-13 Rα1 subunit. Abrezekimab can be used for the research of asthma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号 : 2043952-59-4

容量 価格（税別） 在庫状況 数量
>無料サンプル (100 μg)   今すぐ申し込む  
1 mg $250 在庫あり
5 mg $650 在庫あり
10 mg $1040 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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Interleukin Related アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

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製品説明

Abrezekimab (UCB4144; VR 942) is a humanized, high-affinity, neutralizing anti-human-IL-13 antibody fragment that binds to IL-13. Abrezekimab prevents IL-13 binding to the IL-13 Rα1 subunit. Abrezekimab can be used for the research of asthma[1].

Isotype

Fab-G1-kappa
Species Reactivity

Human
IC50 & Target[1]

IL-13

 

体内実験

Abrezekimab is biophysically stable and well tolerated by the animals in a cynomolgus macaque allergic asthma model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
Gene ID

3596  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

48.1 kDa

CAS 番号
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Abrezekimab]
輸送条件

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Fab-G1-kappa
純度とドキュメンテーション
参考文献
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Abrezekimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Abrezekimab2043952-59-4UCB4144 VR 942UCB 4144UCB-4144VR942VR 942VR-942Interleukin RelatedILasthmaIL-13anti-human-IL-13 antigen-binding FabIL-13 Rα1 subunitInhibitorinhibitorinhibit

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製品名:
Abrezekimab
製品番号:
HY-P99417
数量:
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