1. Anti-infection
  2. Antibiotic
  3. Acetomycin

Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661.

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Acetomycin

Acetomycin Chemical Structure

CAS No. : 510-18-9

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Description

Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661[1].

Cellular Effect
Cell Line Type Value Description References
B16 IC50
4 3
Compound: 4a
Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay
Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay
10.1016/0960-894X(95)00110-F
B16 IC50
4 3
Compound: 4a
Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay
Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay
10.1016/0960-894X(95)00110-F
DA-3 cell line IC50
7 3
Compound: 4a
Tested for cytotoxic activity against DA-3 mouse mammary adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against DA-3 mouse mammary adenocarcinoma cells in MTT assay
10.1016/0960-894X(95)00110-F
HT-29 IC50
5 3
Compound: 4a
Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay
10.1016/0960-894X(95)00110-F
HT-29 IC50
5 3
Compound: 4a
Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay
10.1016/0960-894X(95)00110-F
MCF7 IC50
6 3
Compound: 4a
Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay
10.1016/0960-894X(95)00110-F
MCF7 IC50
6 3
Compound: 4a
Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay
10.1016/0960-894X(95)00110-F
Masse moléculaire

214.22

Formule

C10H14O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1O[C@@H](OC(C)=O)[C@@H](C)[C@]1(C(C)=O)C

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Pureté et documentation
Références
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
Acetomycin
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HY-129564
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