1. GPCR/G Protein Neuronal Signaling Cell Cycle/DNA Damage
  2. Opioid Receptor DNA/RNA Synthesis
  3. Akuammidine

Akuammidine, isolated from the seeds of Picralima nitida, shows a preference for μ-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 μM at μ-, σ- and κ-opioid binding sites, respectively. Akuammidine possesses anti-inflammatory and anti-asthmatic properties.

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Akuammidine

Akuammidine 화학구조

CAS No. : 639-36-1

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제품 설명

Akuammidine, isolated from the seeds of Picralima nitida, shows a preference for μ-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 μM at μ-, σ- and κ-opioid binding sites, respectively. Akuammidine possesses anti-inflammatory and anti-asthmatic properties[1][2].

IC50 & Target

κ Opioid Receptor/KOR

 

In Vitro

Akuammidine treatment decreases the expression of IL-6 in cells[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

352.43

화학식

C21H24N2O3

CAS No.
SMILES

O=C([C@@]1([C@@](CC2=C3NC4=CC=CC=C24)([H])[N@@](C/5)[C@H]3C[C@H]1C5=C/C)CO)OC

Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Akuammidine
Cat. No.:
HY-N7437
수량:
MCE Japan Authorized Agent: