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Antiparasitic agent-14 is a potent antiparasitic agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote.

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Antiparasitic agent-14

Antiparasitic agent-14 화학구조

CAS No. : 3046451-98-0

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Antiparasitic agent-14 Related Antibodies

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제품 설명

Antiparasitic agent-14 is a potent antiparasitic agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote[1].

IC50 & Target

Leishmania

 

Trypanosoma

 

Cellular Effect
Cell Line Type Value Description References
RAW264.7 CC50
295.6 μM
Compound: 27
Cytotoxicity against mouse RAW264.7 cells incubated for 48 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells incubated for 48 hrs by MTT assay
[PMID: 37062170]
In Vitro

Antiparasitic agent-14 (compound 27) shows cytotoxicity and antiparasitic activity with a CC50 value of 295.6 µM for RAW 264.7 cells, IC50 value of 1.5, 0.89 µM for trypomastigote and amastigote forms of Trypanosoma cruzi (T. cruzi), respectively[1].
Antiparasitic agent-14 shows antiparasitic activity against promastigote and amastigote forms of Leishmania amazonensis (L. amazonensis) with IC50 value of 22.4, 5.70 µM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antiparasitic agent-14 Related Antibodies
분자량

352.45

화학식

C19H20N4OS
CAS No.
SMILES

O=C1N(C2=CC=CC=C2)/C(SC1C(C)C)=N\N=C(C3=CC=NC=C3)/C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Antiparasitic agent-14 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiparasitic agent-143046451-98-0Antiparasitic agent14Antiparasitic agent 14ParasitecytotoxicityantiparasitictrypomastigoteamastigotepromastigoteInhibitorinhibitorinhibit

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Antiparasitic agent-14
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HY-149078
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