2. Immunology/Inflammation
  3. Interleukin Related
  4. Avizakimab

Avizakimab  (Synonyms: BOS161721)

Art. -Nr.: HY-P99451 Reinheit: 99.69%
COA
SDS
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Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21.

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CAS. Nr. : 2229685-51-0

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Avizakimab Related Antibodies

Top Publications Citing Use of Products

Alle Interleukin Related Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

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Beschreibung

Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

IL-21
In Vitro

Avizakimab (BOS161721) prevents IL-21 binding to the IL-21 receptor (IL-21R) and inhibits bioactivity[1].
Avizakimab inhibits the downstream signaling, plasma cell differentiation, and natural killer cell activation induced by IL-21 and suppressed antibody responses to keyhole limpet hemocyanin (KLH) antigen[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Avizakimab Related Antibodies
Klinische Studie
Gene ID

59067  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molekulargewicht

145.2 kDa

CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Avizakimab]
Versand

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Reinheit & Dokumentation

Purity: 99.69%

SDS (251 KB)

COA (291 KB) SDS-PAGE (81 KB) SEC-HPLC (133 KB)

Inhibitory Antibodies User Guide (603 KB)
Verweise
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Avizakimab Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Avizakimab2229685-51-0BOS161721BOS 161721BOS-161721Interleukin RelatedILIL-21KLHkeyhole limpet hemocyaninInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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