2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Cathepsin K

Cathepsin K is a cysteine protease with endo and collagenolytic activities. Cathepsin K induces degradation of bone collagen and can be used for the research of osteoporosis.

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Cathepsin K

Cathepsin K 화학구조

CAS No. : 94716-09-3

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Based on 1 publication(s) in Google Scholar

Cathepsin K Related Antibodies

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1 Publications Citing Use of MCE Cathepsin K

View All Cathepsin Isoform Specific Products:

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Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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제품 설명

Cathepsin K is a cysteine protease with endo and collagenolytic activities. Cathepsin K induces degradation of bone collagen and can be used for the research of osteoporosis[1][2].

IC50 & Target

cathepsin K

 

In Vitro

Cathepsin K potently degrades type I collagen, osteonectin, type II collagen, MMP-9, and TGF-β1, with unique triple helix cleavage activity for type I collagen[1].
Cathepsin K (24-96 h) potently degrades type I collagen, achieving full solubilization of adult cortical bone collagen by 96 h, and generates the NTX epitope with complete efficiency, with optimal activity at pH 6.0[2].
Cathepsin K potently degrades the noncollagenous bone matrix protein osteonectin, but does not degrade fibronectin[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cathepsin K Related Antibodies
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Cathepsin K]
선적

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보관

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순도&문서
References
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Cathepsin K Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cathepsin K94716-09-3Cathepsinosteoclaststype II collagentype I collagenInhibitorinhibitorinhibit

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상품명:
Cathepsin K
Cat. No.:
HY-P3153
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