Cholic acid-¹³C

Name: Cholic acid- 13 C
Brand: MedChemExpress
SKU: HY-N0324S2
Rating: 4.5 (0 reviews)

製品番号: HY-N0324S2 純度: 99.17%: Data Sheet SDS COA 取扱説明書
FAQs
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Cholic acid-¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Cholic acid-¹³C 構造式

CAS 番号 : 52886-36-9

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 93	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 93	在庫あり	Estimated Time of Arrival: December 31
Solid
1 mg	$30	在庫あり	Estimated Time of Arrival: December 31
5 mg	$85	在庫あり	Estimated Time of Arrival: December 31
10 mg	$140	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Cholic acid-¹³C:

Cholic acid 在庫あり

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

409.56

分子式

C₂₃¹³CH₄₀O₅

CAS 番号

52886-36-9

Unlabeled CAS

81-25-4

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CC[13C](O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : ≥ 100 mg/mL (244.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4416 mL	12.2082 mL	24.4164 mL
5 mM	0.4883 mL	2.4416 mL	4.8833 mL
10 mM	0.2442 mL	1.2208 mL	2.4416 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.17%

Select Batch:

データシート (273 KB) SDS (251 KB)

COA (251 KB) HNMR (378 KB) CNMR (359 KB) RP-HPLC (382 KB) MS (267 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Li Y, et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684. [Content Brief]

[3]. Pan X, et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.4416 mL	12.2082 mL	24.4164 mL	61.0411 mL
	5 mM	0.4883 mL	2.4416 mL	4.8833 mL	12.2082 mL
	10 mM	0.2442 mL	1.2208 mL	2.4416 mL	6.1041 mL
	15 mM	0.1628 mL	0.8139 mL	1.6278 mL	4.0694 mL
	20 mM	0.1221 mL	0.6104 mL	1.2208 mL	3.0521 mL
	25 mM	0.0977 mL	0.4883 mL	0.9767 mL	2.4416 mL
	30 mM	0.0814 mL	0.4069 mL	0.8139 mL	2.0347 mL
	40 mM	0.0610 mL	0.3052 mL	0.6104 mL	1.5260 mL
	50 mM	0.0488 mL	0.2442 mL	0.4883 mL	1.2208 mL
	60 mM	0.0407 mL	0.2035 mL	0.4069 mL	1.0174 mL
	80 mM	0.0305 mL	0.1526 mL	0.3052 mL	0.7630 mL
	100 mM	0.0244 mL	0.1221 mL	0.2442 mL	0.6104 mL