DL-Glyceraldehyde 3-phosphate 

DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of E. coli. DL-Glyceraldehyde 3-phosphate is a competitive inhibitor of the acyltransferase^[1][2].

DL-Glyceraldehyde 3-phosphate is a time-dependent inhibitor of the cationic and anionic isozymes of aspartate aminotransferase purified from rat liver^[1]. DL-Glyceraldehyde 3-phosphate, an analogue of Glycerol 3-phosphate, enters the cell via the sn-glycerol 3-phosphate transport system and is bactericidal. DL-Glyceraldehyde 3-phosphate is an inhibitor of sn-glycerol 3-phosphate transport^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In vivo, phosphatidylethanolamine and phosphatidylglycerol accumulation are inhibited to the same extent by the addition of DL-Glyceraldehyde 3-phosphate to a culture of E. coli^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

170.06

C₃H₇O₆P

591-59-3

Liquid

Colorless to light yellow

O=CC(O)COP(O)(O)=O

Room temperature in continental US; may vary elsewhere.

Solution, -20°C, 2 years

• [1]. L Kopelovich, et al. Kinetics of the inhibition of aspartate aminotransferase isozymes by DL-glyceraldehyde 3-phosphate. Eur J Biochem. 1971 Jun 11;20(3):351-62.  [Content Brief]

  [2]. C T Tang, et al. L-Glyceraldehude 3-phosphate, a bactericidal agent. Antimicrob Agents Chemother. 1977 Jan;11(1):147-53.  [Content Brief]