2. Metabolic Enzyme/Protease Apoptosis
  3. Endogenous Metabolite Apoptosis
  4. Epoprostenol sodium

Epoprostenol sodium  (Synonyms: Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan)

Cat. No.: HY-A0126A Purity: 98.03%
COA
SDS
Handling Instructions Technical Support

Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation.

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Epoprostenol sodium

Epoprostenol sodium 화학구조

CAS No. : 61849-14-7

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of Epoprostenol sodium:

Epoprostenol sodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Epoprostenol sodium

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Human Endogenous Metabolite Microbial Metabolite

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Epoprostenol (1.0 ng/mL; 24 h) sodium induces apoptosis in PAH-PASMCs by upregulating the expression of IP receptor and Fas ligand (FasL)[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Epoprostenol sodium Related Antibodies
Clinical Trial
분자량

374.45

화학식

C20H31NaO5
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

CCCCC[C@H](O)/C=C/[C@@H]1[C@@]([C@]2([H])C[C@H]1O)([H])C/C(O2)=C/CCCC(O[Na])=O
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

-20°C, sealed storage, away from moisture

*The compound is unstable in solutions, freshly prepared is recommended.

용액&용해도
In Vitro: 

H2O : 25 mg/mL (66.76 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6706 mL 13.3529 mL 26.7058 mL
5 mM 0.5341 mL 2.6706 mL 5.3412 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 98.03%

SDS (393 KB)

COA (253 KB) HNMR (175 KB) RP-HPLC (259 KB) MS (70 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6706 mL 13.3529 mL 26.7058 mL 66.7646 mL
5 mM 0.5341 mL 2.6706 mL 5.3412 mL 13.3529 mL
10 mM 0.2671 mL 1.3353 mL 2.6706 mL 6.6765 mL
15 mM 0.1780 mL 0.8902 mL 1.7804 mL 4.4510 mL
20 mM 0.1335 mL 0.6676 mL 1.3353 mL 3.3382 mL
25 mM 0.1068 mL 0.5341 mL 1.0682 mL 2.6706 mL
30 mM 0.0890 mL 0.4451 mL 0.8902 mL 2.2255 mL
40 mM 0.0668 mL 0.3338 mL 0.6676 mL 1.6691 mL
50 mM 0.0534 mL 0.2671 mL 0.5341 mL 1.3353 mL
60 mM 0.0445 mL 0.2225 mL 0.4451 mL 1.1127 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Epoprostenol sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epoprostenol61849-14-7Prostaglandin I2Prostacyclin FlolanProstaglandin I 2Prostaglandin I-2Endogenous MetaboliteApoptosisInhibitorinhibitorinhibit

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상품명:
Epoprostenol sodium
Cat. No.:
HY-A0126A
수량:
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