2. Anti-infection
  3. Parasite
  4. Eugenitin

Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines.

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Eugenitin

Eugenitin Chemical Structure

CAS No. : 480-12-6

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Eugenitin Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1].

IC50 & Target

LD50: 39.9 μM (Leishmania major)[1]
Cellular Effect
Cell Line Type Value Description References
HCT-8 IC50
>113 μM
Compound: 3
Cytotoxicity against human HCT8 cells by colorimetric method
Cytotoxicity against human HCT8 cells by colorimetric method
[PMID: 24387625]
HL-60 IC50
>113 μM
Compound: 3
Cytotoxicity against human HL60 cells by colorimetric method
Cytotoxicity against human HL60 cells by colorimetric method
[PMID: 24387625]
Lymphocyte IC50
>113 μM
Compound: 3
Cytotoxicity against human lymphocytes by colorimetric method
Cytotoxicity against human lymphocytes by colorimetric method
[PMID: 24387625]
MDA-MB-435 IC50
>113 μM
Compound: 3
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
[PMID: 24387625]
PC-3 IC50
>113 μM
Compound: 3
Cytotoxicity against human PC3 cells by colorimetric method
Cytotoxicity against human PC3 cells by colorimetric method
[PMID: 24387625]
SF-295 IC50
>113 μM
Compound: 3
Cytotoxicity against human SF295 cells by colorimetric method
Cytotoxicity against human SF295 cells by colorimetric method
[PMID: 24387625]
Masse moléculaire

220.22

Formule

C12H12O4
CAS No.
SMILES

O=C1C=C(C)OC2=C1C(O)=C(C)C(OC)=C2
Structure Classification
Initial Source

Mycoleptodiscus indicus
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Eugenitin Related Classifications

  • Calculateur de molarité

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eugenitin480-12-6ParasiteLeishmania majorMycoleptodiscus indicusInhibitorinhibitorinhibit

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Cat. No.:
HY-W663230
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