1. Apoptosis
  2. Bcl-2 Family
  3. F1324 TFA

F1324 TFA is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 TFA exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.

For research use only. We do not sell to patients.

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F1324 TFA Chemical Structure

F1324 TFA Chemical Structure

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Description

F1324 TFA is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 TFA exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].

IC50 & Target

IC50: 1 nM (BCL6)[1]

In Vitro

F1324 TFA binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively[1].
F1324 TFA binds BCL6 not only in cell-free but also cellbased conditions[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1765.04 (free acid)

Formula

C83H121N21O20S.xC2HF3O2

Sequence Shortening

Ac-LWYTDIRMSWRVP-OH

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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F1324 TFA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
F1324 TFA
Cat. No.:
HY-100866A
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