1. Apoptosis
  2. Bcl-2 Family
  3. F1324 acetate

F1324 acetate 

Cat. No.: HY-100866B
Handling Instructions

F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 acetate exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

F1324 acetate Chemical Structure

F1324 acetate Chemical Structure

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Description

F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 acetate exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].

IC50 & Target

IC50: 1 nM (BCL6)[1]

In Vitro

F1324 acetate binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively[1].
F1324 acetate binds BCL6 not only in cell-free but also cellbased conditions[1].

Molecular Weight

1825.09

Formula

C₈₅H₁₂₅N₂₁O₂₂S

Sequence

Ac-{Leu}{Trp}{Tyr}{Thr}{Asp}{Ile}{Arg}{Met}{Ser}{Trp}{Arg}{Val}{Pro}-OH

Sequence Shortening

Ac-LWYTDIRMSWRVP-OH

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

F1324F 1324F-1324Bcl-2 FamilyBCL6protein-proteininteractionPPIInhibitorinhibitorinhibit

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F1324 acetate
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HY-100866B
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