1. Apoptosis
  2. Bcl-2 Family
  3. F1324

F1324 

Cat. No.: HY-100866
Handling Instructions

F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

F1324 Chemical Structure

F1324 Chemical Structure

CAS No. : 2607975-44-8

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Description

F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].

IC50 & Target

IC50: 1 nM (BCL6)[1]

In Vitro

F1324 binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively[1].
F1324 binds BCL6 not only in cell-free but also cellbased conditions[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1765.04

Formula

C₈₃H₁₂₁N₂₁O₂₀S

CAS No.
Sequence Shortening

Ac-LWYTDIRMSWRVP-OH

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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F1324
Cat. No.:
HY-100866
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