2607975-44-8
Chemical Structure
F1324
- CAS No.: 2607975-44-8
- Formula:C83H121N21O20S
- Molecular Weight:1765.04
IUPAC Name: acetyl-L-leucyl-L-tryptophyl-L-tyrosyl-L-threonyl-L-aspartyl-L-isoleucyl-L-arginyl-L-methionyl-L-seryl-L-tryptophyl-L-arginyl-L-valyl-L-proline
InChIKey: LVYIYYGXSDQMMQ-HMIZNXJWSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)NC([C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC5=CNC6=CC=CC=C56)=O
Biological Activity: F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].
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F1324 | F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI. | |||||||||||||||||||||
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Keywords
