GDP-α-D-mannose disodium

Name: GDP-α-D-mannose disodium
Brand: MedChemExpress
SKU: HY-N7389B
Rating: 4.5 (0 reviews)

製品番号: HY-N7389B 純度: 99.76%: Data Sheet SDS COA 取扱説明書
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Technical Support

GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (K_i 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (K_i 115 μM).

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GDP-α-D-mannose disodium 構造式

CAS 番号 : 148296-46-2

容量	価格（税別）	在庫状況	数量
1 mg	$200	在庫あり	Estimated Time of Arrival: December 31
5 mg	$400	在庫あり	Estimated Time of Arrival: December 31
10 mg		お問い合わせ
50 mg		お問い合わせ

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カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of GDP-α-D-mannose disodium:

GDP-D-mannose disodium 在庫あり

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target^[1]

Human Endogenous Metabolite

体外実験

GDP-?α-D-?mannose is the alpha-anomer of GDP-D-mannose.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

649.30

分子式

C₁₆H₂₃N₅Na₂O₁₆P₂

CAS 番号

148296-46-2

Appearance

Solid

Color

White to off-white

SMILES

O=P(OP(O[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)(O[Na])=O)(O[Na])OC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2N3C(N=C(N)NC4=O)=C4N=C3

Structure Classification

Others

Initial Source

Endogenous metabolite

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度

体外:

H₂O : 100 mg/mL (154.01 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5401 mL	7.7006 mL	15.4012 mL
5 mM	0.3080 mL	1.5401 mL	3.0802 mL
10 mM	0.1540 mL	0.7701 mL	1.5401 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.76%

Select Batch:

データシート (273 KB) SDS (394 KB)

COA (252 KB) RP-HPLC (228 KB) LCMS (88 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.5401 mL	7.7006 mL	15.4012 mL	38.5030 mL
	5 mM	0.3080 mL	1.5401 mL	3.0802 mL	7.7006 mL
	10 mM	0.1540 mL	0.7701 mL	1.5401 mL	3.8503 mL
	15 mM	0.1027 mL	0.5134 mL	1.0267 mL	2.5669 mL
	20 mM	0.0770 mL	0.3850 mL	0.7701 mL	1.9252 mL
	25 mM	0.0616 mL	0.3080 mL	0.6160 mL	1.5401 mL
	30 mM	0.0513 mL	0.2567 mL	0.5134 mL	1.2834 mL
	40 mM	0.0385 mL	0.1925 mL	0.3850 mL	0.9626 mL
	50 mM	0.0308 mL	0.1540 mL	0.3080 mL	0.7701 mL
	60 mM	0.0257 mL	0.1283 mL	0.2567 mL	0.6417 mL
	80 mM	0.0193 mL	0.0963 mL	0.1925 mL	0.4813 mL
	100 mM	0.0154 mL	0.0770 mL	0.1540 mL	0.3850 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.