Glycyl-L-leucine

Name: Glycyl-L-leucine
Brand: MedChemExpress
SKU: HY-W016077
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Cat. No.: HY-W016077 Purity: 99.49%: Data Sheet
COA

SDS
Handling Instructions
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Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.

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Glycyl-L-leucine 화학구조

CAS No. : 869-19-2

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	해외재고보유	Estimated Time of Arrival: December 31
Solid
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	해외재고보유	Estimated Time of Arrival: December 31
100 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

or 대량구매 문의

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Glycyl-L-leucine:

Glycyl-L-leucine (Standard) 견적 받기

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•Related Screening Libraries:

•Related Small Molecules:

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View All Endogenous Metabolite Isoform Specific Products:

View All Isoforms

Human Endogenous Metabolite Microbial Metabolite

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.

Cellular Effect

Cell Line	Type	Value	Description	References
MDCK	EC₅₀	0.17 mM Compound: 30	Activation of human PEPT1 expressed in MDCK cells Activation of human PEPT1 expressed in MDCK cells	[PMID: 16759105]
MDCK	IC₅₀	0.07 mM Compound: 30	Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells	[PMID: 16759105]

분자량

188.22

화학식

C₈H₁₆N₂O₃

CAS No.

869-19-2

Appearance

Solid

Color

White to off-white

SMILES

CC(C)C[C@@H](C(O)=O)NC(CN)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

H₂O : 25 mg/mL (132.82 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3129 mL	26.5647 mL	53.1293 mL
5 mM	1.0626 mL	5.3129 mL	10.6259 mL
10 mM	0.5313 mL	2.6565 mL	5.3129 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 50 mg/mL (265.65 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.49%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (245 KB) HNMR (134 KB) RP-HPLC (247 KB)

Handling Instructions (2659 KB)

References

[1]. Ganapathy V, et al. Interaction of amino acids with glycl-L-leucine hydrolysis and transport in monkey small intestine. Clin Sci (Lond). 1979 Dec;57(6):521-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.3129 mL	26.5647 mL	53.1293 mL	132.8233 mL
	5 mM	1.0626 mL	5.3129 mL	10.6259 mL	26.5647 mL
	10 mM	0.5313 mL	2.6565 mL	5.3129 mL	13.2823 mL
	15 mM	0.3542 mL	1.7710 mL	3.5420 mL	8.8549 mL
	20 mM	0.2656 mL	1.3282 mL	2.6565 mL	6.6412 mL
	25 mM	0.2125 mL	1.0626 mL	2.1252 mL	5.3129 mL
	30 mM	0.1771 mL	0.8855 mL	1.7710 mL	4.4274 mL
	40 mM	0.1328 mL	0.6641 mL	1.3282 mL	3.3206 mL
	50 mM	0.1063 mL	0.5313 mL	1.0626 mL	2.6565 mL
	60 mM	0.0885 mL	0.4427 mL	0.8855 mL	2.2137 mL
	80 mM	0.0664 mL	0.3321 mL	0.6641 mL	1.6603 mL
	100 mM	0.0531 mL	0.2656 mL	0.5313 mL	1.3282 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Glycyl-L-leucine Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycyl-L-leucine869-19-2Endogenous MetaboliteInhibitorinhibitorinhibit

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Glycyl-L-leucine

고객리뷰

Other Forms of Glycyl-L-leucine:

Glycyl-L-leucine Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Endogenous Metabolite Isoform Specific Products:

Biological Activity

순도&문서

References

고객리뷰

몰농도 계산기

농도 희석 계산기

Complete Stock Solution Preparation Table

Glycyl-L-leucine Related Classifications

Keywords:

최근 본 상품:

고객리뷰

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report