Homo Sildenafil

Cat. No.: HY-131100 Purity: 98.44%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Homo Sildenafil 화학구조

CAS No. : 642928-07-2

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of Homo Sildenafil:

Homo Sildenafil-d₅ In-stock
Homo Sildenafil (Standard) 견적 받기

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

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View All Phosphodiesterase (PDE) Isoform Specific Products:

View All Isoforms

PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor^[1].

분자량

488.60

화학식

C₂₃H₃₂N₆O₄S

CAS No.

642928-07-2

Appearance

Solid

Color

White to off-white

SMILES

O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC(S(=O)(N4CCN(CC)CC4)=O)=CC=C3OCC)N1

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 50 mg/mL (102.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0467 mL	10.2333 mL	20.4666 mL
5 mM	0.4093 mL	2.0467 mL	4.0933 mL
10 mM	0.2047 mL	1.0233 mL	2.0467 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.44%

Select Batch:

Data Sheet (269 KB) SDS (254 KB)

COA (250 KB) HNMR (282 KB) LCMS (103 KB)

Handling Instructions (2659 KB)

References

[1]. Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0467 mL	10.2333 mL	20.4666 mL	51.1666 mL
	5 mM	0.4093 mL	2.0467 mL	4.0933 mL	10.2333 mL
	10 mM	0.2047 mL	1.0233 mL	2.0467 mL	5.1167 mL
	15 mM	0.1364 mL	0.6822 mL	1.3644 mL	3.4111 mL
	20 mM	0.1023 mL	0.5117 mL	1.0233 mL	2.5583 mL
	25 mM	0.0819 mL	0.4093 mL	0.8187 mL	2.0467 mL
	30 mM	0.0682 mL	0.3411 mL	0.6822 mL	1.7056 mL
	40 mM	0.0512 mL	0.2558 mL	0.5117 mL	1.2792 mL
	50 mM	0.0409 mL	0.2047 mL	0.4093 mL	1.0233 mL
	60 mM	0.0341 mL	0.1706 mL	0.3411 mL	0.8528 mL
	80 mM	0.0256 mL	0.1279 mL	0.2558 mL	0.6396 mL
	100 mM	0.0205 mL	0.1023 mL	0.2047 mL	0.5117 mL

Homo Sildenafil Related Classifications

Endocrinology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Homo Sildenafil642928-07-2Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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Homo Sildenafil

Other Forms of Homo Sildenafil:

Homo Sildenafil Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Phosphodiesterase (PDE) Isoform Specific Products:

Biological Activity

순도&문서

References

고객리뷰

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