2. 天然物
  3. Disease Research Fields Plants Steroids
  4. Liliaceae Other Diseases Anti-aging
  5. Liriope spicata (Thunb.) Lour.
  6. Liriopesides B

Liriopesides B  (Synonyms: Nolinospiroside F)

製品番号: HY-N5135 純度: 99.92%
COA 取扱説明書 Technical Support

Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 87425-34-1

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 119 在庫あり
Solution
10 mM * 1 mL in DMSO USD 119 在庫あり
Solid
5 mg $75 在庫あり
10 mg $110 在庫あり
25 mg $190 在庫あり
50 mg $285 在庫あり
100 mg $420 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of Liriopesides B:

Liriopesides B 関連抗体

Top Publications Citing Use of Products
Apoptosis Analysis
WB
Cell Proliferation/Viability Assay
Cell Migration/Invasion Assay
In Vivo Efficacy Study

    Liriopesides B purchased from MedChemExpress. Usage Cited in: Transl Cancer Res. 2025 Oct 31;14(10):6637-6652.  [Abstract]

    Liriopesides B (LPB) (12, 24 μM) induces apoptosis in SAS and CAL-27 cells.

    Liriopesides B purchased from MedChemExpress. Usage Cited in: Transl Cancer Res. 2025 Oct 31;14(10):6637-6652.  [Abstract]

    The effect of Liriopesides B (LPB) (12, 24 μM) on the protein expression of PI3K, Akt, p-Akt, mTOR, p-mTOR, S6, p-S6, 4EBP1, and p-4EBP1 in SAS cells.

    Liriopesides B purchased from MedChemExpress. Usage Cited in: Transl Cancer Res. 2025 Oct 31;14(10):6637-6652.  [Abstract]

    SC79 reverses the Liriopesides B (LPB) (12, 24 μM)-induced CAL-27 and SAS cells viability inhibition.

    Liriopesides B purchased from MedChemExpress. Usage Cited in: Transl Cancer Res. 2025 Oct 31;14(10):6637-6652.  [Abstract]

    Liriopesides B (LPB) (12, 24 μM) inhibits the invasion ability of SAS and CAL-27 cells.

    Liriopesides B purchased from MedChemExpress. Usage Cited in: Transl Cancer Res. 2025 Oct 31;14(10):6637-6652.  [Abstract]

    The effect of Liriopesides B (LPB) (5, 10 mg/kg) on tumor volume in SAS xenograft nude mice.

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects[1].

    体外実験

    Liriopesides B (Nolinospiroside F) increases SIRT1 activity[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Liriopesides B 関連抗体
    分子量

    722.90

    分子式

    C39H62O12
    CAS 番号
    Appearance

    Solid

    Color

    White to light yellow

    SMILES

    O[C@H]([C@H]([C@H]([C@@H](C)O1)O)O)[C@@H]1O[C@@H]2C[C@H](O[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)CC4=CCC5C6C[C@@]7(O[C@@]8(OC[C@@H](C)CC8)[C@@H](C)[C@@]7([C@]6(CCC5[C@@]24C)C)[H])[H]
    Structure Classification
    Initial Source
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    -20°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
    溶剤 & 溶解度
    体外: 

    DMSO : 100 mg/mL (138.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.3833 mL 6.9166 mL 13.8332 mL
    5 mM 0.2767 mL 1.3833 mL 2.7666 mL
    10 mM 0.1383 mL 0.6917 mL 1.3833 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    体内:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 2.5 mg/mL (3.46 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.5 mg/mL (3.46 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Please enter your animal formula composition:
    %
    DMSO +
    % 
    +
    %
    Tween-80 +
    %
    Saline
    Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
    The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
    Calculation results:
    Working solution concentration: mg/mL
    Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
    Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
     If the continuous dosing period exceeds half a month, please choose this protocol carefully.
    Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
    純度とドキュメンテーション

    純度: 99.92%

    COA (256 KB) HNMR (321 KB) RP-HPLC (241 KB) MS (69 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 1.3833 mL 6.9166 mL 13.8332 mL 34.5829 mL
    5 mM 0.2767 mL 1.3833 mL 2.7666 mL 6.9166 mL
    10 mM 0.1383 mL 0.6917 mL 1.3833 mL 3.4583 mL
    15 mM 0.0922 mL 0.4611 mL 0.9222 mL 2.3055 mL
    20 mM 0.0692 mL 0.3458 mL 0.6917 mL 1.7291 mL
    25 mM 0.0553 mL 0.2767 mL 0.5533 mL 1.3833 mL
    30 mM 0.0461 mL 0.2306 mL 0.4611 mL 1.1528 mL
    40 mM 0.0346 mL 0.1729 mL 0.3458 mL 0.8646 mL
    50 mM 0.0277 mL 0.1383 mL 0.2767 mL 0.6917 mL
    60 mM 0.0231 mL 0.1153 mL 0.2306 mL 0.5764 mL
    80 mM 0.0173 mL 0.0865 mL 0.1729 mL 0.4323 mL
    100 mM 0.0138 mL 0.0692 mL 0.1383 mL 0.3458 mL
    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    Liriopesides B Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Liriopesides B87425-34-1Nolinospiroside FOtherssteroidalsaponinanti-aginganti-oxidativeSIRT1Inhibitorinhibitorinhibit

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    製品名:
    Liriopesides B
    製品番号:
    HY-N5135
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