2. Peptides

Peptides

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Peptides, which are short chains of amino acids linked by peptide bonds, have a variety of biological functions, such as, anti-thrombosis, anti-hypertension, anti-microbial, anti-tumor and anti-oxidation, immune-regulation, and cholesterol-lowering effects. Peptides have been widely used in functional analysis, antibody research, vaccine research, and especially the field of drug research and development.

MedChemExpress (MCE) offers a comprehensive collection of high quality peptides including peptide inhibitors, β-amyloids, therapeutic peptides and amino acid derivatives to clients in pharmaceutical and academic institutions all over the world. Unlimited Custom Peptide Service is also available to help researchers propel their projects.

Peptides

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Peptides (9400):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P11474
    FZ1 peptide 99.92%
    FZ1 peptide is an integrin αvβ3 agonist. FZ1 peptide binds to integrin αvβ3, effectively activates FAK, FAK-dependent AKT and ERK1/2 signaling pathways. FZ1 peptide enhances VEGFC-induced endothelial angiogenesis, accelerates diabetic skin wound healing.
    FZ1 peptide
  • HY-P11497
    Cyclomarin monomer-1 98.24%
    Cyclomarin monomer-1 (Compound 5), a cyclomarin monomer, is a pre-dimerization precursor that can form Homo-BacPROTACs targeting the degradation of ClpC1. Cyclomarin monomer-1 binds to the Mtb ClpC1 protein with a KD of 3.5 nM. The MIC of Cyclomarin monomer-1 against the Mtb H37Rv standard strain is 1.6 μM. Cyclomarin monomer-1 can be used as a key intermediate in the development of Homo-BacPROTACs.
    Cyclomarin monomer-1
  • HY-P1189A
    Echistatin TFA 99.32%
    Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1.
    Echistatin TFA
  • HY-P1259A
    PR-39 TFA 99.89%
    PR-39 TFA, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 TFAreversibly binds to the α7 subunit of the proteasome and blocks degradation of NF-κB inhibitor IκBα by the ubiquitin-proteasome pathway. PR-39 TFA stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice.
    PR-39 TFA
  • HY-P1263A
    tcY-NH2 TFA 1262750-73-1 99.72%
    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology.
    tcY-NH2 TFA
  • HY-P1396A
    GRK2i TFA 99.89%
    GRK2i TFA is a GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. GRK2i TFA corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist.
    GRK2i TFA
  • HY-P1477A
    Adrenocorticotropic hormone (1-39), rat TFA 99.84%
    Adrenocorticotropic hormone (1-39), rat (TFA) is a potent melanocortin 2 (MC2) receptor agonist.
    Adrenocorticotropic hormone (1-39), rat TFA
  • HY-P1485A
    Substance P(1-7) TFA 2828433-22-1 99.14%
    Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) TFA gives depressor and bradycardic effects when applied to the nucleus tractus solitarius.
    Substance P(1-7) TFA
  • HY-P1504A
    β-Melanocyte Stimulating Hormone (MSH), human TFA 99.51%
    β-Melanocyte Stimulating Hormone (MSH), human TFA, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist.
    β-Melanocyte Stimulating Hormone (MSH), human TFA
  • HY-P1525A
    Melanin Concentrating Hormone, salmon TFA 99.91%
    Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.
    Melanin Concentrating Hormone, salmon TFA
  • HY-P1540A
    Angiotensin III, human, mouse TFA 2938960-55-3 99.94%
    Angiotensin III, human, mouse (TFA) is an angiotensin.
    Angiotensin III, human, mouse TFA
  • HY-P1564A
    [Sar1, Ile8]-Angiotensin II TFA 2918768-31-5 99.85%
    [Sar1, Ile8]-Angiotensin II (TFA) is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
    [Sar1, Ile8]-Angiotensin II TFA
  • HY-P1585A
    Gp100 (25-33), human TFA 99.73%
    Gp100 (25-33), human TFA (Hgp100 (25-33) (TFA)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human TFA is a 9-amino acid (AA) epitope restricted by MHC class I H-2Db and recognized by the T cells. Gp100 (25-33), human TFA has immunogenicity and induces specific T cells. Gp100 (25-33), human TFA can be used for the cancer research, such as melanoma.
    Gp100 (25-33), human TFA
  • HY-P1754A
    Tetanus toxin (830-843) TFA
    Tetanus toxin (830-843) TFA is a powerful neurotoxin that reaches by retroaxonal transport and transcytosis the cytoplasm ofspinal inhibitory intemeurons and blocks their ability to release neurotransmitters.
    Tetanus toxin (830-843) TFA
  • HY-P1800A
    Caerulein, desulfated TFA 98.74%
    Caerulein, desulfated TFA is the desulfurated form of Caerulein. Caerulein is a decapeptide having the same five carboxyl-terminal amino acids as gastrin and cholecystokinin (CCK).
    Caerulein, desulfated TFA
  • HY-P1845A
    PACAP-38 (31-38), human, mouse, rat TFA 99.30%
    PACAP-38 (31-38), human, mouse, rat TFA is a fragment containing the C-terminal 31-38 fragment of PACAP (1-38), human, ovine, rat (HY-P0221). PACAP-38 (31-38), human, mouse, rat TFA does not bind to the PACAP receptor.
    PACAP-38 (31-38), human, mouse, rat TFA
  • HY-P1861A
    Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA 98.02%
    Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA, a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU).
    Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA
  • HY-P2196A
    ELA-32(human) TFA 99.93%
    ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
    ELA-32(human) TFA
  • HY-P2336A
    CCZ01048 TFA 98.54%
    CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma.
    CCZ01048 TFA
  • HY-P2624A
    st-Ht31 ammonium
    st-Ht31 ammonium is a membrane-permeable peptide inhibitor of?protein kinase A (PKA) anchoring. st-Ht31 ammonium induces robust cholesterol/phospholipid efflux. st-Ht31 ammonium completely reverses foam cell formation and restores the metabolic health of macrophage.
    st-Ht31 ammonium