Cat. No.: HY-P11474

FZ1 peptide

Customer Review

Based on 1 Customer Validation

FZ1 peptide is an integrin αvβ3 agonist. FZ1 peptide binds to integrin αvβ3, effectively activates FAK, FAK-dependent AKT and ERK1/2 signaling pathways. FZ1 peptide enhances VEGFC-induced endothelial angiogenesis, accelerates diabetic skin wound healing.

For research use only. We do not sell to patients.

Purity: 99.92%
Formula: C₂₉H₄₉N₉O₁₂S₂
Molecular Weight:779.88

Storage:

Sealed storage, away from moisture and light.

Powder -80°C, 2 years , -20°C, 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

FZ1 peptide Chemical Structure

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

αvβ3

ERK1

ERK2

All Integrin Isoforms :

All Akt Isoforms :

All ERK Isoforms :

Chemical Information

Appearance Solid
Molecular Weight 779.88
Formula C₂₉H₄₉N₉O₁₂S₂
Color White to off-white
Sequence

Cys-Lys-Leu-Ser-Asn-Asp-Cys (Disulfide bridge: Cys1-Cys7)
Sequence Shortening

CKLSNDC (Disulfide bridge: Cys1-Cys7)
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (128.22 mM)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.2822 mL

6.4112 mL

12.8225 mL

5 mM

0.2564 mL

1.2822 mL

2.5645 mL

10 mM

0.1282 mL

0.6411 mL

1.2822 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang L, et al. Cyclic Heptapeptide FZ1 Acts as an Integrin αvβ3 Agonist to Facilitate Diabetic Skin Wound Healing by Enhancing Angiogenesis. J Med Chem. 2025 Sep 25;68(18):19503-19520. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O	1 mM	1.2822 mL	6.4112 mL	12.8225 mL	32.0562 mL
	5 mM	0.2564 mL	1.2822 mL	2.5645 mL	6.4112 mL
	10 mM	0.1282 mL	0.6411 mL	1.2822 mL	3.2056 mL
	15 mM	0.0855 mL	0.4274 mL	0.8548 mL	2.1371 mL
	20 mM	0.0641 mL	0.3206 mL	0.6411 mL	1.6028 mL
	25 mM	0.0513 mL	0.2564 mL	0.5129 mL	1.2822 mL
	30 mM	0.0427 mL	0.2137 mL	0.4274 mL	1.0685 mL
	40 mM	0.0321 mL	0.1603 mL	0.3206 mL	0.8014 mL
	50 mM	0.0256 mL	0.1282 mL	0.2564 mL	0.6411 mL
	60 mM	0.0214 mL	0.1069 mL	0.2137 mL	0.5343 mL
	80 mM	0.0160 mL	0.0801 mL	0.1603 mL	0.4007 mL
	100 mM	0.0128 mL	0.0641 mL	0.1282 mL	0.3206 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

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FZ1 peptide

Immunology/Inflammation Compound Library

MAPK Compound Library

PI3K/Akt/mTOR Compound Library

Protein Tyrosine Kinase Compound Library

Stem Cell Signaling Compound Library

Autophagy Compound Library

Anti-Aging Compound Library

Anti-diabetic Compound Library

Macrocyclic Compound Library

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Cytoskeleton Compound Library

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Neuroprotective Compound Library

Anti-Pancreatic Cancer Compound Library

Anti-Cancer Metabolism Compound Library

Angiogenesis-Related Compound Library

Glucose Metabolism Compound Library

Peptide Library

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Osteogenesis Compound Library

Pain-Related Compound Library

Mitochondrial Protection Compound Library

Membrane Protein-targeted Compound Library

Extracellular Vesicles (EVs) Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Peptide Compound Library

Bioactive Compound Library

Protein Kinase Compound Library

Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library

Cell Proliferation Compound Library

High-Throughput Bioactive Compound Library

Lactylation Compound Library

All Integrin Isoforms

All Akt Isoforms

All ERK Isoforms

Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

FZ1 peptide Related Classifications

HY-P11474 Related Classifications