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  3. Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA)

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA) 

Cat. No.: HY-P1861A Purity: 99.73%
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Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA, a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU).

For research use only. We do not sell to patients.

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Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA) Chemical Structure

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA) Chemical Structure

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1 mg USD 50 In-stock
5 mg USD 140 In-stock
10 mg USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA):

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA) Related Antibodies

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Description

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA, a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU)[1].

Molecular Weight

2323.52

Formula

C105H158F3N25O31
Appearance

Solid

Color

White to off-white

Sequence

Ser-Gly-Ile-Pro-Tyr-Ile-Ile-Ser-Tyr-Leu-His-Pro-Gly-Asn-Thr-Ile-Leu-His-Val-Asp
Sequence Shortening

SGIPYIISYLHPGNTILHVD
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 45 mg/mL (19.37 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4304 mL 2.1519 mL 4.3038 mL
5 mM 0.0861 mL 0.4304 mL 0.8608 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.4304 mL 2.1519 mL 4.3038 mL 10.7595 mL
5 mM 0.0861 mL 0.4304 mL 0.8608 mL 2.1519 mL
10 mM 0.0430 mL 0.2152 mL 0.4304 mL 1.0760 mL
15 mM 0.0287 mL 0.1435 mL 0.2869 mL 0.7173 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA)OthersInhibitorinhibitorinhibit

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