Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA

Name: Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA
Brand: MedChemExpress
SKU: HY-P1861A
Rating: 4.5 (0 reviews)

製品番号: HY-P1861A 純度: 98.02%: Data Sheet SDS COA 取扱説明書
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Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA, a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU).

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

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Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA 構造式

容量	価格（税別）	在庫状況	数量
5 mg	$140	在庫あり	Estimated Time of Arrival: December 31
10 mg	$220	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Other Forms of Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA:

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) お問い合わせ

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製品説明

分子量

2323.52

分子式

C₁₀₅H₁₅₈F₃N₂₅O₃₁

Appearance

Solid

Color

White to off-white

Sequence

Ser-Gly-Ile-Pro-Tyr-Ile-Ile-Ser-Tyr-Leu-His-Pro-Gly-Asn-Thr-Ile-Leu-His-Val-Asp

Sequence Shortening

SGIPYIISYLHPGNTILHVD

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

polypeptide, sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (polypeptide, sealed storage, away from moisture and light, under nitrogen)

溶剤 & 溶解度

体外:

H₂O : ≥ 45 mg/mL (19.37 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.4304 mL	2.1519 mL	4.3038 mL
5 mM	0.0861 mL	0.4304 mL	0.8608 mL
10 mM	0.0430 mL	0.2152 mL	0.4304 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 98.02%

Select Batch:

データシート (285 KB) SDS (252 KB)

COA (266 KB) LCMS (121 KB) Elemental Analysis Report (125 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Tang J, et al. Autoimmune uveitis elicited with antigen-pulsed dendritic cells has a distinct clinical signatureand is driven by unique effector mechanisms: initial encounter with autoantigen defines diseasephenotype. J Immunol. 2007 May 1;178(9):5578-87. [Content Brief]

[2]. Cortes LM, et al. Inhibitory peptide analogs derived from a major uveitogenic epitope protect from antiretinalautoimmunity by inducing type 2 and regulatory T cells. J Leukoc Biol. 2008 Aug;84(2):577-85. [Content Brief]

[3]. Yang H, et al. Activation of liver X receptor alleviates ocular inflammation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2014 Apr 28;55(4):2795-804. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.4304 mL	2.1519 mL	4.3038 mL	10.7595 mL
	5 mM	0.0861 mL	0.4304 mL	0.8608 mL	2.1519 mL
	10 mM	0.0430 mL	0.2152 mL	0.4304 mL	1.0760 mL
	15 mM	0.0287 mL	0.1435 mL	0.2869 mL	0.7173 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.