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  4. Methyl oleate

Methyl oleate is a fatty acid methyl ester (FAME) with anti-extended spectrum β-Lactamase (ESBL) potential, anticancer and antibacterial activities. Methyl oleate substantially improves the antioxidation ability but markedly impaired the antiwear capacity of zinc dialkyldithiophosphate (ZDDP). Methyl oleate is promising for research of ESBL producing multi drug resistant (MDR) pathogens.

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Methyl oleate

Methyl oleate Chemische Struktur

CAS. Nr. : 112-62-9

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10 mM * 1 mL in DMSO
ready for reconstitution
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Other Forms of Methyl oleate:

Methyl oleate Related Antibodies

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Beschreibung

Methyl oleate is a fatty acid methyl ester (FAME) with anti-extended spectrum β-Lactamase (ESBL) potential, anticancer and antibacterial activities. Methyl oleate substantially improves the antioxidation ability but markedly impaired the antiwear capacity of zinc dialkyldithiophosphate (ZDDP). Methyl oleate is promising for research of ESBL producing multi drug resistant (MDR) pathogens[1][2][3].

In Vitro

Methyl oleate (80, 100 μg/mL) is effective in inhibiting ESBL producing MDR E. coli and K. pneumoniae[2].
Methyl oleate (25 μg-800 μg, 48 h) exerts an inhibition of A549 cells with an IC50 value of 625 μg/mL[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Methyl oleate Related Antibodies

Cell Viability Assay[2]

Cell Line: A549 cells
Concentration: 25 μg-800 μg
Incubation Time: 48 h
Result: Lost the cell ability to proliferate by inhibiting cell to cell contact at 24 h and at 48 h all the cells become smaller in size.
In Vivo

Methyl oleate (50-200 mg/L, mixed in water, a single dose for 96 h) treats the 96 h lethal concentrations obtained for Lobeo rohita with a LC50 value of 50 mg/L[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lobeo rohita[2]
Dosage: 50-200 mg/L
Administration: mixed in water, a single dose for 96 h
Result: Displayed behavioural responses such as hyperventilation, motionless state, increase opercular ventilation, general body weakness, skin discoloration, loss of reflex, erratic swimming, and movement in response to the test chemical in fish.
Molekulargewicht

296.49

Formel

C19H36O2
CAS. Nr.
Appearance

Liquid (Density: 0.874 g/cm3)

Color

Colorless to off-white

SMILES

CCCCCCCC/C=C\CCCCCCCC(OC)=O
Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 33.33 mg/mL (112.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3728 mL 16.8640 mL 33.7280 mL
5 mM 0.6746 mL 3.3728 mL 6.7456 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.57%

SDS (775 KB)

COA (237 KB) HNMR (251 KB) MS (70 KB) GC (250 KB)

Handling Instructions (2659 KB)
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3728 mL 16.8640 mL 33.7280 mL 84.3199 mL
5 mM 0.6746 mL 3.3728 mL 6.7456 mL 16.8640 mL
10 mM 0.3373 mL 1.6864 mL 3.3728 mL 8.4320 mL
15 mM 0.2249 mL 1.1243 mL 2.2485 mL 5.6213 mL
20 mM 0.1686 mL 0.8432 mL 1.6864 mL 4.2160 mL
25 mM 0.1349 mL 0.6746 mL 1.3491 mL 3.3728 mL
30 mM 0.1124 mL 0.5621 mL 1.1243 mL 2.8107 mL
40 mM 0.0843 mL 0.4216 mL 0.8432 mL 2.1080 mL
50 mM 0.0675 mL 0.3373 mL 0.6746 mL 1.6864 mL
60 mM 0.0562 mL 0.2811 mL 0.5621 mL 1.4053 mL
80 mM 0.0422 mL 0.2108 mL 0.4216 mL 1.0540 mL
100 mM 0.0337 mL 0.1686 mL 0.3373 mL 0.8432 mL
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Methyl oleate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyl oleate112-62-9Environmental PollutantsBacterialEnvironmental ContaminantsFAMEESBLZDDPInhibitorinhibitorinhibit

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