1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
  3. N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)

N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)  (Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium)

Cat. No.: HY-112582C Purity: 99.70%
Handling Instructions Technical Support

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)

N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) 화학구조

CAS No. : 3056945-59-3

사이즈 가격 재고 수량
Solvent
5.64 mg (100 mM * 100 μL in water) 해외재고보유
Solvent
11.28 mg (100 mM * 200 μL in water) 해외재고보유
Solvent
28.21 mg (100 mM * 500 μL in water) 해외재고보유
Solvent
56.41 mg (100 mM * 1 mL in water) 해외재고보유

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM):

Top Publications Citing Use of Products

1 Publications Citing Use of MCE N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)

View All DNA/RNA Synthesis Isoform Specific Products:

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability[1].

In Vitro

N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) is used to synthesize mRNAs with lower immunogenicity and higher stability[1].
Modified mRNAs synthesized from N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) can be delivered to the heart[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

564.11

화학식

C10H14N2Na3O15P3

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O

선적

Shipping with dry ice.

보관

-80°C

용액&용해도
In Vitro: 

H2O : 100 mg/mL (177.27 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7727 mL 8.8635 mL 17.7270 mL
5 mM 0.3545 mL 1.7727 mL 3.5454 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.70%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7727 mL 8.8635 mL 17.7270 mL 44.3176 mL
5 mM 0.3545 mL 1.7727 mL 3.5454 mL 8.8635 mL
10 mM 0.1773 mL 0.8864 mL 1.7727 mL 4.4318 mL
15 mM 0.1182 mL 0.5909 mL 1.1818 mL 2.9545 mL
20 mM 0.0886 mL 0.4432 mL 0.8864 mL 2.2159 mL
25 mM 0.0709 mL 0.3545 mL 0.7091 mL 1.7727 mL
30 mM 0.0591 mL 0.2955 mL 0.5909 mL 1.4773 mL
40 mM 0.0443 mL 0.2216 mL 0.4432 mL 1.1079 mL
50 mM 0.0355 mL 0.1773 mL 0.3545 mL 0.8864 mL
60 mM 0.0295 mL 0.1477 mL 0.2955 mL 0.7386 mL
80 mM 0.0222 mL 0.1108 mL 0.2216 mL 0.5540 mL
100 mM 0.0177 mL 0.0886 mL 0.1773 mL 0.4432 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

최근 본 상품:

온라인 문의

Your information is safe with us. * Required Fields.

상품명

 

Requested Quantity *

고객명 *

 

호칭

메일주소 *

 

전화번호 *

Department

 

회사명 *

City

Country or Region *

     

비고

대량구매 문의

Inquiry Information

상품명:
N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)
Cat. No.:
HY-112582C
수량:
MCE Japan Authorized Agent: